{"title":"Anti-cancer","description":"","products":[{"product_id":"gut-defend-probiotic","title":"Gut Defend Probiotic","description":"\u003cp\u003eThe GI tract is a finely balanced environment where roughly 500 different strains of bacteria compete for space and nutrients.\u003c\/p\u003e\u003cp\u003eWhen there is a healthy balance (eubiosis), few symptoms exist. However, dysbiosis can occur when an overabundance of potentially harmful organisms prevail. The natural microflora balance can be upset by medications (such as antibiotics, oral contraceptives, etc.), excessive alcohol consumption, or poor\u003c\/p\u003e\u003cp\u003edietary intake.\u003c\/p\u003e\u003cp\u003eProbiotics have been extensively studied and are characterized as having broad GI and immune benefits, including (1) increasing the population of healthy bacteria following microflora imbalance; (2) supporting healthy bowel function; (3) increasing the production of short-chain fatty acids, which provide energy to the cells of the intestinal lining; (4) strengthening the gut-immune barrier by promoting a healthy gut mucosa; (5) aiding in the digestion of difficult-to-breakdown like lactose and casein; and (6) enhancing detoxification of harmful compounds.\u003c\/p\u003e\u003cp\u003eBecause probiotics are live organisms, there are many challenges associated with manufacturing and distributing\u003c\/p\u003e\u003cp\u003eprobiotic supplements. For a probiotic to be effective, it must be shelf-stable through the expiration date and preciselydelivered to the intestinal tract, where it can have maximum benefit. BioShield® technology is an innovative manufacturing process developed to ensure consistent and reliable results. The microorganisms in this product are protected, sealed and freeze dried away from moisture, heat, light and oxygen. This allows the bacteria to remain dormant until they are exposed to moisture in the GI tract. By utilizing advanced encapsulation\u003c\/p\u003e\u003cp\u003etechnology, the probiotic organisms are preserved and released on-target for maximum benefit.\u003c\/p\u003e\u003cp\u003eLactobacillus acidophilus (La-14)†\u003c\/p\u003e\u003cp\u003eLactobacillus acidophilus is a beneficial bacterial strain that is normally found in the intestinal tract and mouth and is commercially used in dairy products for the production of acidophilus-type yogurt. L. acidophilus ferments various carbohydrates to produce lactic acid, which increases the absorption and bioavailability of minerals. This includes calcium, copper, magnesium and manganese. The production of lactic acid also promotes health by creating an inhospitable environment for invading microbes.1 L. acidophilus has been shown to protect intestinal cells by competing for adhesion space in the gut against harmful bacteria, such as E. coli. The L. acidophilus strain in this product has been specifically chosen because of its strong adherence and survival attributes in the GI tract. It has been demonstrated in vitro to tolerate exposure to gastric acid and bile salts, and has the ability to withstand antibiotics including Ciproflaxin, Polymyxin B and Tetracycline.2\u003c\/p\u003e\u003cp\u003eLactobacillus paracasei (Lpc-37)†\u003c\/p\u003e\u003cp\u003eLactobacillus paracasei has been shown to protect against the harmful effects of bacteria such as Staphylococcus aureus (S. aureus).3 L. paracasei colonizes the intestinal tract by reinforcing defense mechanisms that support an immune response. It does this by supporting T-helper cell production and secreting secretory IgA (sIgA), an antibody critical for supporting intestinal immunity.4 L. paracasei Lpc-37 is a gastric acid-resistant strain and has been shown in vitro to withstand antibiotics such as Ciproflaxin and Vancomycin.5\u003c\/p\u003e\u003cp\u003eBifidobacterium bifidum (Bb-02)†\u003c\/p\u003e\u003cp\u003eBifidobacterium bifidum has been shown to effectively compete with harmful bacteria such as E. coli, S. aureus and\u003c\/p\u003e\u003cp\u003eCamplylobacter jejuni, which suggests B. bifidum’s lactic acid and acetic acid production provides an antagonistic action against pathogens to help maintain microflora balance.6\u003c\/p\u003e\u003cp\u003eBifidobacterium lactis (BI-04)†\u003c\/p\u003e\u003cp\u003eBifidobacterium lactis is predominantly found in the colon. A double-blind, randomized placebo-controlled trial on subjects receiving B. lactis or placebo for eight weeks found that B. lactis supported a balanced immune response in individuals hypersensitive to environmental allergens.7 Studies examining immune development and dietary supplementation with B. lactis have shown that it supports GI health by reducing\u003c\/p\u003e\u003cp\u003eintestinal permeability.8\u003c\/p\u003e\u003cp\u003eLactobacillus plantarum (Lp-115)†\u003c\/p\u003e\u003cp\u003eLactobacillus plantarum is a beneficial bacteria commonly found in fermented foods including sauerkraut, pickles,\u003c\/p\u003e\u003cp\u003ebrined olives and sourdough. L. plantarum has been found to compete against strains of Clostridium difficile and Clostridium perfringens, due to the production of bacteriocins (lethal proteins) that inhibit bacterial growth.9 Studies have also demonstrated that L. plantarum helps boost the immune response by stimulating Th1-mediated immunity.10\u003c\/p\u003e\u003cp\u003eLactobacillus rhamnosus (Lr-32)†\u003c\/p\u003e\u003cp\u003eLactobacillus rhamnosus has been proven to have remarkable survivability in the acid and bile environments in the GI tract. L. rhamnosus is particularly useful because of its ability to adhere to cells, enhance microflora balance, and inhibit pathogen adherence. L. rhamnosus was also found to positively affect inflammatory and immune gene signaling of over 1,700 genes when administered in high doses.11\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCaution \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eIf you are pregnant or nursing, consult your physician\u003c\/p\u003e\u003cp\u003ebefore taking this product.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740315234552,"sku":"6","price":102.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/853435359.jpg?v=1780291479"},{"product_id":"gut-health-cleanse-wormwood-olive-leaf-extract-and-berberine","title":"Gut Health Cleanse Wormwood, Olive Leaf Extract and Berberine","description":"\u003cp\u003eFormulated with the goal of supporting the gastrointestinal (GI) flora by promoting balanced immunity, the plant compounds in this product also provide potent antioxidant support, to help fend off microbial challenges. The ingredients in This product help to maintain a healthy GI environment by supplying botanicals shown to create a hostile environment for pathogenic microbes. Each capsule of this product includes sweet wormwood (150 mg), olive leaf extract (100 mg), black walnut hulls (85 mg) and artemisinin (25 mg).\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOverview:\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eOverview Gastrointestinal health is directly affected by factors, such as exposure to microbes, poor diet and a stressful lifestyle, that can negatively impact immune function. The prevalence of refined sugars and carbohydrates and the low presence of fiber in the modern diet has been directly linked to the alteration of the colonic environment.1 Since the body’s immune system is a complex and dynamic defense system, healthy microbial balance and antioxidant support help ensure more optimal immune function. Maintaining healthy microbial balance is not only integral to optimal GI health, but also supports overall health and well-being. This product provides a blend of plant compounds which work together to defend against microbial stressors. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWormwood\/Artemisinin\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eWormwood is a fern-like plant commonly found throughout Asia, and artemisinin is its active constituent. Artemisinin is a sesquiterpene lactone, a special compound shown to have strong microbial-balancing properties. It is known to interfere with microbial metabolism by causing structural changes to unfriendly organisms that prevent them from maturing in the body. This effect is facilitated by the production of free radicals and reactive aldehydes within the microbes that disrupt their growth.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOlive Leaf Extract\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eWidely consumed in the Mediterranean, olives contain numerous phenolic compounds, including oleuropein, which have demonstrated broad spectrum microbial-balancing and antioxidant properties. Oleuropein is a unique polyphenol molecule in olive leaf extract and special processing techniques now allow for the extraction of a stable, standardized form of oleuropein. Oleuropein is a potent antioxidant, supports microbial balance, and helps maintain a healthy cycle of inflammation in the body. Studies have indicated that oleuropein boosts host immune defense and it is especially helpful in supporting those with microbial challenges related to microbial imbalances in the intestines. In one in vitro study, phenolic compounds from olive leaf, including oleuropein, were able to interfere the cellular metabolism of a wide range of microbes creating a hostile environment to their survival. Another study found olive leaf extract prevents cell-to-cell attachment in a dose-dependent manner, a key mechanism in supporting healthy microbial balance.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBlack Walnut†\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe hulls of the black walnut have been used since Greek and Roman times to support those with intestinal complaints. Black walnut has compounds known as tannins, which affect the structural stability of various microbes. The activity (minimum inhibitory concentration) of four different tannin containing plants was determined by broth dilution method, and black walnut was found to be the most active against various microbes.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBerberine Sulfate\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eBerberine is an alkaloid extracted from plant roots that is commonly found in barberry, turmeric and Oregon grape. Berberine extracts have shown significant ability to influence the activity of a variety of organisms that affect human health. In vitro, berberine has been found to promote GI health10 and, among 25 patients, 5 mg\/kg per day of berberine for six days promoted positive changes in the microbial samples of 17 patients. Mechanisms of action for berberine include effects on organism adhesion and intracellular interference, metabolic activity, maturation and free radical formation. By addressing the intestinal secretion of water and electrolytes induced by certain organism toxins, berberine also supports the healthy formation of stool. In this way, it promotes healthy intestinal motility and normal intestinal transit time. Both in vitro and animal research suggest berberine can also affect COX-2 protein, promoting a balanced cycle of inflammation.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e Directions\u003c\/strong\u003e 1 capsule three times per day or as recommended by your health care professional.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740315267320,"sku":"f34481335bef","price":94.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2253572088.jpg?v=1780291480"},{"product_id":"histfx-vitamin-c-quercetin-and-stinging-nettles-leaf","title":"HistFx Vitamin C, Quercetin and Stinging Nettles Leaf","description":"\u003cp\u003eThis product is a targeted blend of flavonoids, antioxidants, proteolytic enzymes and botanicals designed to provide comprehensive support for seasonal challenges caused by common environmental allergens. Natural D- Hist includes quercetin, a powerful flavonoid, to support healthy histamine levels. Bromelain enhances the absorption of quercetin and supports mucosal tissue health. Stinging nettles leaf balance hyper-immune response and N-acetyl cysteine clear the airways by promoting normal viscosity of mucus. This powerful combination actively promotes healthy nasal and sinus passages for individuals with elevated histamine and respiratory irritation. Also available in convenient blister packs.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOverview: \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eQuercetin\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eQuercetin is a biologically active flavonoid antioxidant that is widely distributed in plants including oak trees, onions and tea. Quercetin has strong antioxidant activity and has been shown to support immune health by mediating the release of inflammatory compounds including leukotrienes and prostaglandins. Quercetin is known for its ability to stabilize mast cells, diminishing the release of histamine, the compound known to cause hypersensitivity reactions during seasonal changes. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eStinging Nettles Leaf\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eUrtica dioica, commonly known as stinging nettles, is a plant that has been shown to balance immune response, specifically in the airways and nasal passages. Studies have shown that the extract of stinging nettles leaf balances a variety of inflammatory activities that affect respiratory health. Stinging nettles leaf controls mast-cell degranulation, prostaglandin formation, and histamine action all contributing to a balanced inflammatory response. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBromelain\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eBromelain is a plant enzyme naturally found on the stem and fruit of the pineapple plant. Bromelain is a proteolytic enzyme that aids in in the breakdown of large protein complexes, including antigenic compounds, and has been shown to enhance the absorption of quercetin. Bromelain has been shown to reduce circulating allergenic protein complexes associated with hyper-immune sensitivity and seasonal discomfort.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eN-Acetyl Cysteine\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eN-acetyl cysteine (NAC) is an amino acid precursor to one of the most important antioxidants in the body, glutathione. Both glutathione and NAC help reduce the viscosity of the mucus allowing for clearing of the airways and improved respiratory health. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eVitamin C\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eVitamin C cannot be synthesized by humans and is therefore an essential nutrient that must be consumed in the diet. Among its numerous health-promoting properties, vitamin C is an essential vitamin that supports the immune system and is also a potent antioxidant. When the body is under a significant amount of stress, both emotional and environmental, vitamin C is excreted rapidly. Vitamin C has many immune boosting properties, but is distinctively beneficial for individuals with seasonal discomfort because of its ability to deactivate histamine. \u003c\/p\u003e\u003cp\u003eDirections: \u003c\/p\u003e\u003cp\u003eLoading Dose: 2 capsules three times per day for 7-10 days or as recommended by your health care professional. \u003c\/p\u003e\u003cp\u003eMaintenance: 2 or more capsules per day or as recommended by health care professional.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740315300088,"sku":"5d1627c9aeac","price":92.4,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2253570679.jpg?v=1780291481"},{"product_id":"optimum-immune-bakers-yeast-extract","title":"Optimum Immune Bakers Yeast Extract","description":"\u003cp\u003eA strong immune system is integral to overall health and wellbeing.\u003c\/p\u003e\u003cp\u003eMaintaining a strong immune system can often be a challenge in today’s world- high stress levels, poor diet, lack of sleep and environmental pollutants can slow down immune response. This product’s primary active ingredient is Wellmune WGP®- a natural beta 1,3\/1,6 glucan derived from the cell wall of a proprietary strain of baker’s yeast (Saccharomyces cerevisiae).\u003c\/p\u003e\u003cp\u003eOnce swallowed, immune cells in the gastrointestinal tract take up Wellmune WGP® and transport it to immune organs throughout the body. Specific immune cells called macrophages digest Wellmune WGP® into smaller fragments and slowly release them over a number of days. The fragments then bind to neutrophils (white blood cells), via complement receptor 3 (CR3). Neutrophils are the most abundant immune cells in the body, accounting for 60-70% of all immune cells.\u003c\/p\u003e\u003cp\u003eThe activation of neurotrophils by Wellmune WGP® fragments allows these cells to move faster throughout the body, resulting in a significant boost in immune defense.\u003c\/p\u003e\u003cp\u003eWellmune WGP® \u003c\/p\u003e\u003cp\u003eBeta-glucan has been recognized for its support of immune system activity for centuries [1] and has become the subject of over 800 scientific studies. Wellmune WGP® has been shown in clinical studies to have a potent effect on immune responsiveness and to defend the system from the effects of recurring stress. Numerous studies have shown betaglucan also promotes production of antioxidant enzymes and supports immune function against microbes. [2] In a study of 54 firefighters given Wellmune WGP® or placebo, those who took\u003c\/p\u003e\u003cp\u003eWellmune WGP® experienced better physical health and nearly 25% reported fewer upper respiratory challenges. A 2013 study on healthy women given 250 mg Wellmune WGP® or placebo also found 10% fewer upper respiratory challenges compared to placebo; better well-being and mental and physical energy levels were also reported.[3] In another randomized, placebocontrolled, double-blind study on the effects of four weeks of 250 mg Wellmune WGP® or 250 mg per day of rice flour placebo on the physical and psychological health of those with seasonal discomfort symptoms, Wellmune WGP® improved symptoms, overall physical health and emotional well-being, compared to placebo.[4] Further research on medical students found a 22% reduction in the total number of days with upper respiratory symptoms in Wellmune WGP® group versus placebo. Finally, a 28-day lifestyle study found that participants taking Wellmune WGP® reported a 34% improvement in health scores after four weeks compared with the control group as well as increased vigor, and lower fatigue, confusion and tension. Wellmune WGP® has also been found to provide post exercise protection,\u003c\/p\u003e\u003cp\u003eCautions \u003c\/p\u003e\u003cp\u003eIf you are pregnant or nursing, consult with your health care practitioner before taking this product.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740318904568,"sku":"0","price":38.7,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2225799698.jpg?v=1780291498"},{"product_id":"power-greens-greens-veggies-fruit-and-antioxidants","title":"Power Greens Greens, Veggies, Fruit and Antioxidants","description":"\u003cp\u003eCausenta®’s Power Greens is formulated to provide a convenient source of indispensable phytonutrients, antioxidants, fiber, and digestive enzymes to complement a healthy diet and lifestyle. A colorful blend of organic health-promoting “superfoods” have been incorporated into this all-natural greens and reds drink for their phytonutrient content and support of antioxidant activity. Truebroc™ from broccoli seed extract is added for long-lasting antioxidant and detoxification support. Probiotics, fiber, and digestive enzymes augment gastrointestinal health, absorption, and utilization of nutrients in this comprehensive superfood blend. Organic flavoring and natural sweeteners (stevia and Luo Han Guo) make Power Greens not only healthful but great tasting, as well.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOrganic Fiber Blend \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eOrganic gum acacia, inulin, and flaxseeds provide a total of 3 g of dietary fiber per scoop of Power Greens to support gastrointestinal function and probiotic activity as well as to assure multiple health benefits from increased dietary fiber intake.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOrganic Greens and Veggies Blend \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eOrganic carrots, green cabbage, broccoli, beets, chlorella, and spinach provide concentrated sources of folate, chlorophyll, carotenoids, and a multitude of phytonutrients that promote health and fight disease. The greens in Power Greens are naturally alkalizing. An alkaline pH is needed for optimal metabolic, enzymatic, repair, and immune functions in the body.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAntioxidant Support\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eAscorbic acid, organic astragalus root, organic ginger root, and organic lycium berry extract provide an antioxidant rich foundation to protect tissues from free-radical damage and promote cellular health. OxyPhyte® Ultra Blend (white tea leaf extract, apple fruit extract, and rosemary leaf extract) provides antioxidant support. In fact, in a preclinical bioavailability trial, results suggested that this blend increased serum antioxidant levels in human subjects.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOrganic Fruits and Berries Blend\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eOrganic apple juice powder, strawberry juice powder, sea buckthorn juice powder, açai, acerola fruit extract, plum fruit extract, and blueberry concentrates provide additional antioxidant capacity and health-promoting phytonutrients.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003etruebroc™ Broccoli Seed Extract \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003etruebroc provides a concentrated source of sulforaphane glucosinolate, also known as glucoraphanin. Glucoraphanin is a phytochemical precursor to sulforaphane, a naturally occurring isothiocyanate in broccoli that supports and promotes antioxidant and detoxification activity.Scientists at Johns Hopkins University School of Medicine identified glucoraphanin (GR) and sulforaphane (SFN) as the “missing links” that correlate a diet rich in cruciferous vegetables with the maintenance of good health. Broccoli sprouts and seeds provide higher concentrations of GR than the mature vegetable. Glucoraphanin is converted to SFN via the action of myrosinase, an enzyme in broccoli that is released during chewing, cutting, or slicing. Microorganisms can also convert GR to SFN; the presence of probiotics and broccoli in Power Greens may enhance this conversion in the body. Research suggests that GR and SFN provide long-lasting antioxidant and detoxification support that may improve overall health and well-being.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDigestive Support Blend \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eProbiotic organisms L acidophilus, B longum, L casei, and L rhamnosus are present to maintain a healthy gastrointestinal microflora. A healthy microflora provides gastrointestinal and immune support and helps to moderate and eliminate pathogenic bacteria. Digestive enzymes (protease, amylase, bromelain, cellulase, lactase, papain, and lipase) in Power Greens assist in the breakdown of carbohydrates, fats, proteins, and lactose to enhance nutrient digestion and availability. Power Greens can be consumed by itself or as an accompaniment to any smoothie or protein drink. The inclusion of phytonutrient-rich superfoods, OxyPhyte Ultra Blend, and truebroc creates an innovative and ideal formula for antioxidant support.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740320837880,"sku":"728b08230e8f","price":87.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2264108103.jpg?v=1780291504"},{"product_id":"sleep-performance-valerian-root-and-l-theanine","title":"Sleep Performance Valerian Root and L-Theanine","description":"\u003cp\u003e\u003cstrong\u003eDiscussion\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHuman Studies\u003c\/strong\u003e A Home Use Test (HUT) performed in 2005 among a target group of 61 men and women using SLEEP PRO II for two weeks yielded very positive results.\u003csup\u003e[1]\u003c\/sup\u003e Seventy-four percent of respondents used the product according to the directions: Take seven or more capsules during the two-week test period. Of these respondents,\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e83% said SLEEP PRO II helped them relax*\u003c\/li\u003e\n\u003cli\u003e91% said SLEEP PRO II helped reduce fatigue due to lack of sleep*\u003c\/li\u003e\n\u003cli\u003e91% said SLEEP PRO II helped ensure a good night’s sleep*\u003c\/li\u003e\n\u003cli\u003e82% said SLEEP PRO II is an essential item to have on hand*\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eAn open-label, single-center, observational survey that included 295 people (ages 18-87) with sleep difficulties was performed to obtain a subjective evaluation of the tolerability and effectiveness of SLEEP PRO II.\u003csup\u003e[2]\u003c\/sup\u003e Self-reported sleep difficulties included problems falling asleep, multiple wakings, and next-day tiredness due to a lack of sleep. Patients taking at least one 365 mg capsule of SLEEP PRO II one hour before going to bed every night for at least two weeks experienced the following:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e86% considered SLEEP PRO II relaxing*\u003c\/li\u003e\n\u003cli\u003e82.8% said SLEEP PRO II assisted in a restful sleep*\u003c\/li\u003e\n\u003cli\u003e82.8% said SLEEP PRO II was effective in reducing fatigue due to lack of sleep*\u003c\/li\u003e\n\u003cli\u003eNo significant adverse events\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eSLEEP PRO II (known as SEDITOL®) is a blend of a patented extract of Magnolia officinalis bark and a proprietary extract of Ziziphus spinosa seed. These herbs have been traditionally used in Asia for qì stagnation, for mild anxiety and nervousness, and to support normal, uninterrupted sleep.*\u003csup\u003e[3-5] \u003c\/sup\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eMagnolia officinalis\u003c\/strong\u003e Magnolia bark is rich in a biphenol compound called honokiol and its isomer magnolol. In experimental animal studies, these compounds have been shown to enhance the activity of gamma-aminobutyric acid (GABA) A receptors and GABA binding, which may help the body cope with the neurologic effects emotions can have on behavior and well-being.\u003csup\u003e[4,6]\u003c\/sup\u003e Honokiol, administered by intraperitoneal injection in mice, was shown to promote NREM (non-rapid eye movement) sleep by modulating the benzodiazepine site of the GABA (A) receptor.\u003csup\u003e[5]\u003c\/sup\u003e And, in an experimental animal model of chronic mild stress, a mixture of honokiol and magnolol supported normal levels of 5-hydroxytryptamine (5-HT) and its metabolite 5-hydroxyindoleacetic acid (5-HIAA) in various brain regions. The combination also promoted healthy corticosterone levels and platelet adenylyl cyclase (AC) activity. Researchers suggest that these findings provide a basis for further study into the influence of magnolol and honokiol on the serotonergic system, the HPA (hypothalamic-pituitary-adrenal) axis, and the AC-cAMP pathway in relation to mood and emotional behavior.*\u003csup\u003e[7]\u003c\/sup\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eZiziphus spinosa\u003c\/strong\u003e A primary use of Z spinosa seeds in Traditional Chinese Medicine is to support calmness and help individuals with occasional sleeplessness.\u003csup\u003e[8,9]\u003c\/sup\u003e In an experimental animal model, saponins and flavonoids extracted from the seeds showed a significant relaxing effect and helped prolong sleeping time.\u003csup\u003e[8]\u003c\/sup\u003e To investigate potential mechanisms, researchers tested the influence of spinosin—a flavonoid derived from ziziphus seeds—on pentobarbital-induced sleep in mice. They concluded that it potentiated sleep via a serotonergic mechanism.*\u003csup\u003e[10] \u003c\/sup\u003e\u003c\/p\u003e\u003cp\u003eKoetter et al\u003csup\u003e[3]\u003c\/sup\u003e studied the interactions of magnolia and ziziphus extracts with selected central nervous system receptors in a series of assays. Interactions with the adenosine A1 receptor, dopamine transporter and dopamine D5 receptor (antagonist activity), serotonin receptors (5-HT1B and 5-HT6 antagonist activity), and the GABA benzodiazepine receptor were demonstrated. It is suggested that these findings provide some insight into the combined activity of these extracts.*\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDirections\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eTake one to two capsules before bedtime, or as directed by your healthcare practitioner.\u003c\/p\u003e\u003cp\u003eConsult your healthcare practitioner before use. Do not use if pregnant or lactating. Do not use if tamper seal is damaged.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e1. Seditol sleep supplement. HUT: Final report. TRG Study #82-05013. Nanuet, NY: Target Research Group; April, 2005. Study on file.\u003c\/p\u003e\u003cp\u003e2. LaValle J, Pelletier M, LaValle L, et al. A proprietary blend of Magnolia and Ziziphus extracts assists with sleep: an open-label assessment.\u003c\/p\u003e\u003cp\u003e3. Koetter U, Barrett M, Lacher S, et al. Interactions of Magnolia and Ziziphus extracts with selected central nervous system receptors. J Ethnopharmacol. 2009 Jul 30;124(3):421-25. [PMID: 19505549]\u003c\/p\u003e\u003cp\u003e4. Alexeev M, Grosenbaugh DK, Mott DD, et al. The natural products magnolol and honokiol are positive allosteric modulators of both synaptic and extra-synaptic GABA(A) receptors. Neuropharmacology. 2012 Jun;62(8):2507-14. [PMID: 22445602]\u003c\/p\u003e\u003cp\u003e5. Qu WM, Yue XF, Sun Y, et al. Honokiol promotes non-rapid eye movement sleep via the benzodiazepine site of the GABA(A) receptor in mice. Br J Pharmacol. 2012 Apr 27. doi: 10.1111\/j.1476-5381.2012.02010.x. [Epub ahead of print] [PMID: 22537192]\u003c\/p\u003e\u003cp\u003e6. Squires RF, Ai J, Witt MR, et al. Honokiol and magnolol increase the number of [3H] muscimol binding sites three-fold in rat forebrain membranes in vitro using a filtration assay, by allosterically increasing the affinities of low-affinity sites. Neurochem Res. 1999 Dec;24(12):1593-602. [PMID: 10591411]\u003c\/p\u003e\u003cp\u003e7. Xu Q, Yi LT, Pan Y, et al. Antidepressant-like effects of the mixture of honokiol and magnolol from the barks of Magnolia officinalis in stressed rodents. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Apr 1;32(3):715-25. [PMID: 18093712]\u003c\/p\u003e\u003cp\u003e8. Jiang JG, Huang XJ, Chen J, et al. Comparison of the sedative and hypnotic effects of flavonoids, saponins, and polysaccharides extracted from Semen Ziziphus jujube. Nat Prod Res. 2007 Apr;21(4):310-20. [PMID: 17479419]\u003c\/p\u003e\u003cp\u003e9. Peng WH, Hsieh MT, Lee YS, et al. Anxiolytic effect of seed of Ziziphus jujuba in mouse models of anxiety. J Ethnopharmacol. 2000 Oct;72(3):435-41. [PMID: 10996283]\u003c\/p\u003e\u003cp\u003e10. Wang LE, Bai YJ, Shi XR, et al. Spinosin, a C-glycoside flavonoid from semen Zizhiphi Spinozae, potentiated pentobarbital-induced sleep via the serotonergic system. Pharmacol Biochem Behav. 2008 Sep;90(3):399-403. [PMID: 18466960]\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDoes Not Contain\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eWheat, gluten, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically-modified organisms (GMOs) artificial colors, artificial sweeteners, or preservatives.\u003c\/p\u003e\u003ctable class=\"ecwid-description-table\"\u003e\u003ctbody\u003e\u003ctr\u003e\u003cth\u003e\u003cstrong\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/strong\u003e\u003c\/th\u003e\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740322050296,"sku":"a5d069f3dad7","price":70.2,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2253596243.jpg?v=1780291507"},{"product_id":"yeast-health-cleanse-berberine-oregano-and-ginger","title":"Yeast Health Cleanse Berberine, Oregano and Ginger","description":"\u003cp\u003eGastrointestinal health is directly affected by factors like poor diet and a stressful lifestyle. The prevalence of refined sugars and carbohydrates and lack of fiber in modern diets have been directly linked to changes in the intestinal and colonic environments. Since more than 70% of the body’s immune system resides in the gut, establishing a healthy microbial balance is critical in reducing immune challenges and maintaining inflammatory balance. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBiotin\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eBiotin is a water-soluble vitamin and cofactor for carboxylases. The nutrient affects several key systemic functions such as tissue growth, development, immunity and metabolism. Deficiencies in biotin have also been linked with mild immune impairment. Biotin establishes microflora balance in the GI tract by preventing yeast, especially Candida albicans, from converting to its more invasive fungal form. In the presence of biotin, yeast is unable to change into the mycelium form\u003cstrong\u003e. \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOregano\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003ePhytonutrients from oregano, such as rosmarinic acid and quercetin, have been shown to play a role in supporting antioxidant mechanisms and healthy microbial balance in the body. In addition, the high ORAC (oxygen radical absorbance capacity), on a scale developed by scientists at the National Institute of Aging) value of oregano, indicates its significant antioxidant-scavenging capacity to combat free radicals that cause oxidative stress. Oregano oil also contains two naturally occurring microbial balancing agents, named carvacrol and thymol. Research suggests that these compounds relieve GI dysbiosis and promote a healthy GI microflora. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePau D’Arco\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe inner portion of the Pau D’Arco bark has been used by Native Americans for thousands of years to support intestinal microbial health. The botanical has been shown to be effective in promoting healthy intestinal flora and is recommended by herbalists for a wide variety of GI challenges. Studies have shown that Pau d’Arco may also balance musculoskeletal inflammation and in-vitro studies have shown fractions from Pau D’Arco support microbial balance.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eZinc Undecylenate\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eUndecylenic acid has been used to support microbial and immune balance in a variety of different microbial challenges. Studies show undecyclenic acid to inhibit morphogenesis of Candida albicans; the compound also appears to interfere with fatty acid biosynthesis, inhibiting germ tube (hyphae) formation and disrupting the pH in yeast cells. Of the medium chain fatty acids, undecylenic acid has also been shown to provide strong support for microbial balance and is approximately six times more potent than caprylic acid.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSodium Caprylate\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eSodium caprylate is the stable sodium salt of caprylic acid, a fatty acid found in coconuts. In vitro studies show that sodium caprylate inhibits aerobic and anaerobic growth, provokes loss of cytoplasm organization and organelles, inhibits budding, triggers potassium loss and is destructive to the cellular integrity of Candida albicans. Caprylic acid has been shown to contribute to microbial balance and to increase cell telomere size to a desirable 750 ng BDORT.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBerberine HCl\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eAn alkaloid extracted from plant roots, berberine has been found to express strong microbe balancing activity In vitro, and was found to be the best of four agents studied in inhibition of Candida albicans’ adherence to HT-29 epithelial cells. Berberine was also found to inhibit SAP (secreted aspartyl proteinases) activity by 70.2% +\/-6%, a marker of yeast conversion to the aggressive fungal form. In one invitro study, mice given 1 mg\/kg body weight of berberine saw an increase in microbial balance[17] and displayed synergistic effects with fungal balancing agents.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eRosemary\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe essential oil of rosemary has been shown to exhibit broad spectrum microbial balancing effects. The oil was analyzed in vitro microbial balancing and antioxidant was found to have strong activity. Rosemary extract has also been shown to decrease oxidative stress in various tissues.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCinnamon Bark Extract\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eIn an invitro study looking at different strains of microbes, including MRSA and Candida species, the essential oil of cinnamon showed consistent ability to maintain microbial balance. Invitro research has shown that cinnamon extract causes a change in cell morphology, destruction of organelles and cellular burst in microbes.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDirections: \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e2 capsules three times per day or as recommended by your health care professional.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740325228792,"sku":"3315a363ca75","price":118.8,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2253662581_0a95bf76-6c6c-4e20-9e76-9c034849927d.jpg?v=1780291513"}],"url":"https:\/\/causenta.com\/collections\/anti-cancer.oembed","provider":"Causenta","version":"1.0","type":"link"}