{"title":"Vitamins \u0026 Supplements","description":"","products":[{"product_id":"adrenal-support-cordyceps-and-rhodiola","title":"Adrenal Support Cordyceps and Rhodiola","description":"\u003cp\u003e\u003cstrong\u003eCordyceps sinensis (cordyceps)\u003c\/strong\u003e \u003c\/p\u003e\u003cp\u003eAs a highly regarded cornerstone of Chinese medicine, cordyceps has been used for centuries for its far-reaching restorative effects. It is a safe, highly valued herb with activities that support nearly every physiological system impacted by the body’s response to normal everyday stressors, including the immune and cardiovascular systems. Cordyceps has been used to support good balance, strength, and a healthy body weight. It is also widely and traditionally used to increase energy and enhance stamina. It has a positive effect on blood sugar and fat metabolism, which is important because fats and sugars are actively mobilized during activation of the stress response to supply the body with extra energy. Traditional Chinese Medicine (TCM) practitioners also recommend the regular use of cordyceps to strengthen the body. Furthermore, the cell-protective and antioxidant activities of cordyceps have been documented.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eRhodiola rosea (rhodiola)\u003c\/strong\u003e \u003c\/p\u003e\u003cp\u003eThis adaptogenic herb has been used traditionally in Eastern Europe and Asia for centuries to increase stamina, maintain a healthy mood, support the nervous and immune systems, and maintain healthy male sexual function. According to Panossian et al, experimental studies performed on isolated organs, tissues, cells, and enzymes demonstrate that rhodiola preparations exhibit adaptogenic effects that support nerve, brain, and heart health and are calming, longevity-enhancing, and central nervous system-stimulating. In addition, experimental animal models suggest that the root extract may be able to support normal heart rhythm. Rhodiola may also have a positive effect on brain neurotransmitters, such as dopamine and serotonin, and may influence endogenous opioid levels. According to a review of the literature on rhodiola, supplementation supports healthy work performance, quality of sleep, appetite, and energy levels subsequent to intense physical or intellectual strain. Salidrosides and rosavin have been identified as primary actives. The rhodiola extract in this formula is standardized to provide no less than 1%-3% salidrosides and 3% rosavin.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePanax ginseng (ginseng)\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e\u003c\/strong\u003e As an important herbal remedy in TCM, ginseng has been used for thousands of years, primarily for energy production. The main active agents have been identified as ginsenosides, and they are the focus of much published research. Experimental models show that ginseng and ginsenosides have beneficial effects in supporting the adrenal glands; protecting the gastric mucosa; and supporting healthy body weight, blood hormones, and the gene expression of catecholamine-synthesizing enzymes. Ginsenosides also have immune-supporting and cytokinemodulating activities.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eVitamin B6, Pantothenic Acid, and Para-Aminobenzoic Acid (PABA)\u003c\/strong\u003e \u003c\/p\u003e\u003cp\u003ePantothenic acid is essential to the adrenal glands for production of the glucocorticoids. It forms pantethine in the body, which then converts to coenzyme-A—the most active metabolic enzyme in the human body needed to produce cellular energy. D-calcium pantothenate contains 91.96% pantothenic acid and is the usual supplemental form. Vitamin B6, acting as a coenzyme, has a role in the conversion of muscle glycogen to glucose, which is needed for a proper response to stressors; the synthesis of serotonin; and the support of the immune function. PABA has a role in amino acid metabolism and is needed to manufacture folic acid.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eThe Thyroid Connection\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe interplay between healthy adrenal function and healthy thyroid function has long been recognized by functional medicine practitioners. In fact, cortisol acts in concert with thyroid hormone at the receptor-gene level, and a normal physiologic amount of cortisol is important for normal thyroid function.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDirections: \u003c\/strong\u003eTake one capsule twice daily, or as directed by your healthcare practitioner. Consult your healthcare practitioner prior to use. Individuals taking medication should discuss potential interactions with their healthcare practitioner. \u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740309074168,"sku":"b55629c2321a","price":57.6,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2225767099.jpg?v=1780291462"},{"product_id":"anti-ox-glucoraphanin-and-curcumin","title":"Anti Ox Glucoraphanin and Curcumin","description":"\u003cp\u003eThis product is a unique combination of phytonutrients designed to enhance antioxidant potential by stimulating nuclear factor-erythroid-2-related factor 2 (Nrf2), a dynamic pathway known to increase the production of the body’s most important cellular antioxidants. This unique combination of truebroc™, turmeric, pterostilbene, and resveratrol provides potent free radical scavenging potential, balancing of key inflammatory associated pathways, and induction of intracellular antioxidant production. These powerful phytochemicals are the basis of many “superfoods” and have extensive, peer-reviewed research supporting their dramatic effect on cell health and longevity.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOverview: \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eNrf2 is a transcription factor that regulates the antioxidant response of the body. It is the primary cellular defense against the cytotoxic effects of oxidative stress. This key protein is found inside a cell and is inactive until it is released by an Nrf2 activator. Once activated, Nrf2 migrates into the nucleus and binds to DNA at the location of the master antioxidant regulator, the antioxidant response element (ARE). Studies suggest Nrf2 plays an important role in supporting the activation of cellular antioxidant systems, as well as inflammatory balance. A number of fruit and vegetable compounds have been shown to activate Nrf2 and ARE, and increase antioxidant potential. It is believed that these compounds have a protective effect on the body, help maintain a healthy cycle of inflammation, and induce cellular longevity.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBroccoli Seed Extract\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e Broccoli seed extract has the highest levels of glucoraphanin (a potent Nrf2 stimulator) of any broccoli product available. In fact, 230 mg of broccoli seed extract is equivalent to consuming 1 ¼ cups of fresh broccoli. Glucoraphanin is a phytochemical compound that acts as the precursor to sulforaphane, one of the leading compounds in broccoli that is responsible for many of its positive benefits. These compounds and their mechanisms have been studied extensively and supported by more than 500 scientific publications. Glucoraphanin and sulforaphane act as direct activators of Nrf2 and potent antioxidants shown to support detoxification and inflammatory balance. Studies show they work by improving hormone balance and increasing functional enzymes that support excretion of toxins from the body. Broccoli seed extract has been shown to remain active within the body for up to three days following consumption.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTurmeric Root Extract\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eTurmeric is a bright orange-colored spice used for thousands of years in cooking and medicine. Through its antioxidant mechanisms, the active ingredient in turmeric, curcumin, helps to maintain a healthy cardiovascular system, support gastrointestinal (GI) health, and provide neuroprotective activity. Curcumin has been shown to play a crucial role in maintaining proper inflammatory balance in a variety of bodily systems due to its ability to modulate Nrf2. Studies have shown curcumin supports the maintenance of balanced inflammation in endothelial cells and cardiac cells. Curcumin has also been found to provide antioxidant protection to the cardiovascular system by reducing oxidative stress and supporting a normal immune response.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePterostilbene\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eStilbenes make up a subgroup of phytochemicals that have potent antioxidant properties. Pterostilbene is a specific stilbene found in plant varieties like deerberry, rabbiteye blueberries, unripe pinot noir grapes, Botrytis vinifera-infected Chardonnay grapes and Xarello grapes. Through activation of Nrf2, in vitro studies show pterostilbene significantly enhances expression of antioxidant enzymes, such as heme oxygenase-1 (HO-1) and glutathione reductase (GR). Some studies have shown antioxidant benefits may be improved when pterostilbene is combined with curcumin and resveratrol.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eResveratrol\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eResveratrol, like pterostilbene, is a stilbene found in many plants and red wines. It is the most well-researched stilbene. Studies of resveratrol have found it to enhance the potential of antioxidant and detoxification activity through Nrf2 activation. Other studies have linked resveratrol to enhancing blood sugar balance, balancing inflammation and reducing oxidative stress.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDirections\u003c\/strong\u003e 2 capsules per day or as recommended by your health care professional.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740309893368,"sku":"46b70cbd270b","price":75.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2253545200.jpg?v=1780291464"},{"product_id":"bergamot-max","title":"Bergamot Max","description":"\u003cp\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003cstrong\u003eBergamot Max\u003c\/strong\u003e features a highly concentrated source of polyphenolic antioxidants derived from bergamot (Citrus bergamia), a flavonoid-rich fruit originating from the Calabria region in southern Italy and traditionally used to support cardiovascular wellness. Research has suggested that Bergamot Polyphenolic Fraction Gold (BPFG®) is utilized hepatically to help maintain healthy cholesterol levels already within normal range and to support healthy blood glucose metabolism.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740310286584,"sku":"82","price":62.4,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2266764813.jpg?v=1780291466"},{"product_id":"bone-support-mchc-calcium-and-magnesium","title":"Bone Support MCHC, Calcium and Magnesium","description":"\u003cp\u003eMore than 20 years of scientific research have given the name Ossopan worldwide recognition as a source of microcrystalline hydroxyapatite concentrate (MCHC). Numerous published studies support the safety, tolerability, and bone health-related effectiveness of MCHC supplementation. Studies suggest that the bioavailability of calcium from MCHC supplements may be as good as or better than the bioavailability of calcium from calcium gluconate supplements. Causenta® utilizes standardized, safe, bovine-sourced MCHC from New Zealand, a country with stringent standards. Its production features a proprietary technique that preserves the bioactive contents of bone. This process creates a naturally balanced formula because whole bone extract provides all of the nutrients found in healthy bone.\u003c\/p\u003e\u003cp\u003eUnlike other calcium supplements on the market, Ossopan consists of collagenous and non-collagenous proteins and peptides. These compounds include insulin-like growth factors I and II (IGF-I, IGF-II), transforming growth factor beta (TGF-beta), and osteocalcin, factors that stimulate alkaline phosphatase activity and support metabolism in human bone cells. Removal of the protein fraction appears to reduce the positive effects of the formula, highlighting the importance of its presence.\u003c\/p\u003e\u003cp\u003eTake two capsules with meals, twice daily, or as directed by your healthcare practitioner.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740310941944,"sku":"21333ac5fac8","price":63.6,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2266737516.jpg?v=1780291467"},{"product_id":"boswellia-plus-salicin-and-boswellia","title":"Boswellia Plus Salicin and Boswellia","description":"\u003cp\u003eBoswellia Plus is formulated to support eicosanoid and cytokine balance and provide support for joint comfort. 5-LOXIN®, a patented Boswellia extract yielding concentrated 3-O-acetyl-11-keto-ß-boswellic acid (AKBA), is found to inhibit the 5-lipoxygenase enzyme. Salicin from white willow bark is a natural inhibitor of both the COX-2 and 5-lipoxygenase enzymes. Bioflavonoid-rich BerryVin™ provides additional support for eicosanoid balance and antioxidant activity.* \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWhite Willow Bark (Salix alba)\u003c\/strong\u003e Willow bark has been used for thousands of years to help support eicosanoid and cytokine balance and to help relieve discomfort.[1-3] Willow bark is currently approved by the German Commission E and the European Scientific Cooperative on Phytotherapy (ESCOP) for these purposes. Willow bark is also recognized in the United States for its role in supporting joint comfort.[1] Willow bark contains glycosides, salicylates, flavonoids, tannins, aromatic compounds, and acids. A 2007 Cochrane review of the literature found moderate evidence that Salix alba positively affected eicosanoid metabolism and produced results that were comparable to those obtained by other commonly used compounds. Favorable results were obtained when the Salix alba in the studies was standardized to 120 mg or 240 mg salicin. Boswellia Plus provides a standardized 120 mg dose of salicin per serving.*[4] \u003c\/p\u003e\u003cp\u003eVarious randomized placebo-controlled studies suggest that willow bark produces positive effects on joint discomfort. The usual dose of salicin is 240 mg per day,[5] which is the intake recommendation for Boswellia Plus. Pharmacokinetic evaluations reveal that salicylic acid is the major metabolite of salicin, though other components of willow bark are believed to provide relief as well.[6] The mechanism of action of white willow bark appears to involve an effect on both arachidonic acid-derived eicosanoids and cytokine compounds.*[7] \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e5•Loxin®,\u003c\/strong\u003e a standardized Boswellia serrata extract enriched to 30% 3-O-acetyl-11-keto-ß-boswellic acid (AKBA), is ten times more concentrated than ordinary B serrata. Boswellia serrata is an ayurvedic herb whose principle constituents— boswellic acid and alpha-boswellic acid—may help maintain healthy leukotriene metabolism by reducing the activity of the enzyme 5-lipoxygenase.[8] 5-lipoxygenase (5-LOX) catalyzes the synthesis of unfavorable leukotrienes.* \u003c\/p\u003e\u003cp\u003eA randomized, double-blind, placebo-controlled trial assessing the efficacy, safety, and tolerability of Boswellia extract produced statistically significant and clinically relevant decreases in knee discomfort, increases in knee flexion, and increases in walking distance.[9] A randomized, double-blind, placebo-controlled study specifically designed with 5•Loxin resulted in statistically significant improvements in comfort and physical function and a significant reduction in matrix metalloproteinase (MMP) in synovial fluid.[10] MMP represents a class of enzymes that selectively hydrolyze peptide bonds and degrade structural proteins; they play a crucial role in the degradation of joint tissues. 5•Loxin shows significant inhibition against several MMPs. It helps prevent the formation of human recombinant TNF-α inducible MMPs, which further facilitates the maintenance of healthy cartilage and cell-cycle regulation.*[11,12] \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBerryVin™\u003c\/strong\u003e (40 mg) contains a blend of blueberries, strawberries, escobillo, and cranberries, along with grape and pomegranate extracts. This bioflavonoid-rich berry powder provides polyphenols, anthocyanins, ellagic acid, and an antioxidant capacity of 4000 TE\/g to fight free radicals. It may also provide substantial antioxidant support for soft tissues. Bioflavonoids are thought to act synergistically to inhibit cyclooxygenases, lipoxygenases, and phospholipases, ultimately supporting healthy eicosanoid metabolism and favorable cytokine balance.*[13,14]\u003c\/p\u003e\u003cp\u003eTake two capsules twice daily, or as directed by your healthcare practitioner.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740311269624,"sku":"2130980cdf44","price":50.4,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2280770258.jpg?v=1780291468"},{"product_id":"buffered-c-capsules","title":"Buffered C Capsules","description":"\u003cp\u003e\u003cstrong\u003eBuffered C\u003c\/strong\u003e \u003cstrong\u003eCapsules \u003c\/strong\u003eare balanced with calcium, magnesium and potassium to gently deliver high-concentration vitamin C to reduce the potential of gastrointestinal upset.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740311826680,"sku":"83","price":46.8,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2280751677.jpg?v=1780291469"},{"product_id":"curcumin-max","title":"Curcumin Max","description":"\u003cp\u003e\u003cstrong\u003eCurcumin Max \u003c\/strong\u003eis a full-spectrum turmeric product that contains an exclusive blend of bioactive nutrients. It is a natural turmeric matrix standardized to contain curcuminoids, turmeric oils and turmerin protein, along with many other active turmeric compounds that deliver comprehensive support. This formula provides comprehensive benefits and supports healthy breathing, cognitive function, gut and immune function.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740312252664,"sku":"84","price":73.8,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2281120757.jpg?v=1780291471"},{"product_id":"digestion-support","title":"Digestion Support","description":"\u003cp\u003e\u003cstrong\u003eDigestion Support\u003c\/strong\u003e is a comprehensive blend of acid-resistant, plant-based enzymes designed to help maximize the digestion and absorption of nutrients from food. Each capsule includes lipase, amylase, lactase, CereCalase® and protease to aid in the digestion of protein, fat, starches, fiber and other difficult to digest foods known to cause food sensitivities. CereCalase®, a special blend of hemicellulase, beta-glucanase and phytase, is specially formulated to digest the cell walls of plants, providing better nutrition from a plant-based diet. \u003cspan\u003e\u003cstrong\u003eDigestion Support\u003c\/strong\u003e\u003c\/span\u003e also includes Gentian root, a traditional bitter herb, and artichoke, a natural choleretic, added to stimulate the body’s natural production of enzymes and bile.\u003c\/p\u003e\u003cp\u003eDigestive enzymes have a long history of use for those who need digestive enzyme support. In the past, animal enzymes were preferred to vegetable enzymes for their protein digesting strength though they required a narrower pH window of 6.5-7.5 in order to be activated. \u003cstrong\u003e\u003cspan\u003e\u003cspan\u003eDigestion Support\u003c\/span\u003e\u003c\/span\u003e \u003c\/strong\u003e\u003cstrong\u003e\u003c\/strong\u003eutilizes new, plant- based enzymes which function within a broader pH range of 2.5-8.5, and still offer the digestive strength of animal-based enzymes. This broad pH window of activity makes it especially helpful for individuals with lower gastric acid levels or inconsistent pH’s. Each enzyme has been tested in pH, temperature, and gastric survivability studies to ensure enzyme activity. In addition, \u003cspan\u003e\u003cspan\u003e\u003cstrong\u003eDigestion Support\u003c\/strong\u003e\u003c\/span\u003e\u003c\/span\u003e also includes DPP4, one of the primary components of peptidase, which has been shown to digest and neutralize gluten. This action may help to support gluten-sensitive individuals who ingest it inadvertently. The blend of proteases in \u003cstrong\u003e\u003cspan\u003eDigestion Support\u003c\/span\u003e \u003c\/strong\u003eis also effective in breaking down proteins from soy, whey, and casein from milk products. Lipases for fat breakdown as well as amylases for carbohydrate breakdown are also included for full- spectrum digestive support.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740312678648,"sku":"85","price":79.2,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2281097411.jpg?v=1780291472"},{"product_id":"estro-performance-calcium-d-glucarate-i3c-and-dim","title":"Estro Performance Calcium D-Glucarate, I3C and DIM","description":"\u003cp\u003eThis product is a targeted supplement that combines the synergistic benefits of the cruciferous vegetable metabolites Indole-3-carbinol (I3C) and diindolylmethane (DIM) to support proper estrogen metabolism. Formulating I3C and DIM together creates the ideal combination of beneficial metabolites to support estrogen balance and breast and prostate health.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOverview: \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eEstrogen collectively refers to the female hormones estradiol, estrone and estriol. Hormones have important functions in every area of the body. They are chemical messengers that interact with cells all over the body (especially tissues that are more sensitive to them, including breast and prostate tissues). The most important message they deliver to cells is to grow, divide and multiply. For this reason, hormones are critically important in human development and tissue repair. Supporting proper estrogen synthesis, metabolism and detoxification is essential for proper hormonal balance. The means in which estrogen is metabolized can result in different metabolites, each with individual biological activity. By keeping hormones in balance and ensuring the body is able to process hormones properly, cruciferous vegetable metabolites (such as I3C and DIM) work together to reduce hormone overload and maintain cellular health. Current data on I3C and DIM suggests that these phytonutrients have strong potential for supporting breast, cervical, uterine and prostate health. Together, I3C and DIM promote the creation of the favorable and protective 2-hydroxyestrone (2-OHE) metabolite versus production of 4-hydroxyestrone (4-OHE) and 16-alpha-hydroxyestrone (16-alphaOHE), metabolites which can overstimulate cells and create free radicals that cause DNA damage. The influence of I3C and DIM on estrogen metabolism creates a more desirable ratio of 2-OHE to 16-alpha-OHE. This assessment of 2:16-alphaOHE ratio has been used to evaluate breast health. With this in mind, this product includes targeted doses of both I3C and DIM in one capsule per day dosing to make daily balancing of hormones easy and convenient. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eI3C I3C (indole-3-carbinol)\u003c\/strong\u003e is a naturally occurring compound found in numerous cruciferous vegetables, such as broccoli, cauliflower, kale and cabbage. Following ingestion of I3C, the body converts it to several different metabolites, one of which is diindolylmethane (DIM). Both of these compounds, as well as many other I3C metabolites, have been shown to impact metabolic shifts and cellular activities for improved health outcomes. I3C has also been shown to temper estrogen signals by competing for binding sites and inhibiting the activity of estrogen receptors. A study published in the Journal of Nutrition unveiled evidence that I3C supports healthy cellular function related to estrogen metabolism.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDIM† Diindolylmethane (DIM)\u003c\/strong\u003e is a phytonutrient and plant indole also found in cruciferous vegetables with potential for enhancing proliferation of healthy cells and cellular activities. As a dimer (formed chemical structure of two substances) of indole-3-carbinol, DIM promotes beneficial estrogen metabolism in both sexes supporting the formation of healthy estrogen metabolites and enhancing the potential for greater antioxidant activity.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCalcium D-Glucarate Calcium D-Glucarate \u003c\/strong\u003eis the supplemental calcium salt form of D-glucaric acid, a substance produced naturally in the body and obtained through consumption of certain fruits and vegetables. 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The gut microbiome is spoken about frequently, but less commonly discussed are the specific microbiomes contained in other areas such as the skin, the lungs, the mouth, and even the vagina. The vaginal microbiome is abundant in \u003cem\u003eLactobacillus\u003c\/em\u003e species, as they contribute heavily to the production of lactic acid. The lactic acid maintains a pH of 4, which if elevated, is a risk for vaginal microbiome challenges. 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This allows for higher dosing of the active ingredient, which helps maintain a healthy mucosal surface.\u003c\/div\u003e\u003cdiv\u003e\u003cstrong\u003e\u003cem\u003eAloe Vera Leaf Gel Extract\u003c\/em\u003e\u003c\/strong\u003e\u003c\/div\u003e\u003cdiv\u003eA demulcent that has been used throughout history, aloe vera has long been known to maintain normal inflammatory balance.\u003c\/div\u003e\u003cdiv\u003e\u003cstrong\u003e\u003cem\u003eL-Glutamine\u003c\/em\u003e\u003c\/strong\u003e\u003c\/div\u003e\u003cdiv\u003eL-glutamine is a main source of fuel for the cells of the small intestines and essential to tissue repair throughout the body.\u003c\/div\u003e\u003cdiv\u003e\u003cstrong\u003e\u003cem\u003eN-Acetyl Glucosamine\u003c\/em\u003e\u003c\/strong\u003e\u003c\/div\u003e\u003cp\u003eN-acetyl glucosamine is the acetylated form of glucosamine. It is a mucin precursor and has been shown to increase the production of mucus within the GI tract.\u003c\/p\u003e\u003cdiv\u003e\u003cstrong\u003e\u003cem\u003eZinc\u003c\/em\u003e\u003c\/strong\u003e\u003c\/div\u003e\u003cp\u003eZinc is an essential mineral widely recognized for its role in gut and immune health. Zinc has been shown to strengthen GI barrier function by supporting the structure of tight junctions.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740314775800,"sku":"86","price":80.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2281131079.jpg?v=1780291476"},{"product_id":"great-workout-vitamin-b12-green-tea-extract-and-caffeine","title":"Great Workout Vitamin B12, Green tea extract and Caffeine","description":"\u003cp\u003e\u003cstrong\u003eOverview: \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePURENERGY™\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003ePurenergy is an innovative patent-protected ingredient that combines caffeine with pTeroPure® pterostilbene—a highly bioavailable analog of resveratrol—to form a unique co-crystal structure. It appears that this unique structure affects the way the body utilizes caffeine. As such, it may offer significant advantages over caffeine alone.\u003c\/p\u003e\u003cp\u003eStudy Findings\u003c\/p\u003e\u003cp\u003eIn a rat study, the half-life of the caffeine from Purenergy was eight hours, while that of ordinary caffeine was just three hours. In a preliminary, four-week, single-blind, crossover human study that compared 232 mg of Purenergy (providing 99.76 mg of caffeine) to 100 mg of ordinary caffeine, the following effects were demonstrated: \u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e Purenergy delivered almost 30% more caffeine into the blood than ordinary caffeine.\u003c\/li\u003e\n\u003cli\u003e The absorption rate of the caffeine from Purenergy was significantly slower by approximately 30% compared to ordinary caffeine.\u003c\/li\u003e\n\u003cli\u003e The half-life of the caffeine from Purenergy was extended significantly by approximately 25% compared to ordinary caffeine.\u003c\/li\u003e\n\u003cli\u003e At 4 hours, serum showed 45% more caffeine from Purenergy compared to ordinary caffeine.\u003c\/li\u003e\n\u003cli\u003eAt 6 hours, serum showed 51% more caffeine from Purenergy compared to ordinary caffeine.\u003c\/li\u003e\n\u003cli\u003ePurenergy had no adverse effect.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eWhile the results of these studies are promising, larger studies are needed to validate the findings and determine if these findings translate into a lengthened energy effect.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eMore Energy\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eTaken together, data from these studies suggest that the effects of caffeine from Purenergy may last longer than the effects from ordinary caffeine and point to a potential for reducing total caffeine intake due to Purenergy’s more efficient delivery and slower absorption rate. These are encouraging factors for people who wish to reduce their caffeine intake.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSlower Caffeine “Finish” \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eScientists are researching whether or not the extended half-life and slower absorption rate of caffeine from Purenergy can produce a more moderated and gradual finish. This may help prevent the “crash” associated with regular caffeinated energy products and may give Great Workout an advantage over formulas that use ordinary caffeine.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAll-Natural, No Sugars\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eGreat Workout relies on natural ingredients, not ephedra or artificial stimulants. Furthermore, it provides only five grams of carbohydrates and zero sugars. By using natural flavors and stevia in place of sugar and other carbohydrates, the typical “sugar high” that is associated with many energy drinks can be avoided. Equally important, Great Workout contains no artificial colors.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCaffeine, in General\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eIn animal and human studies, caffeine has demonstrated positive effects on athletic performance, fatigue, and cognitive functions, such as supporting a healthy memory. According to Meeusen et al, research on caffeine suggests its performance-enhancing effect is related to antagonism of the adenosine receptors that influence the dopaminergic and other neurotransmitter systems.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePterostilbene \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eIn the aforementioned human study, Purenergy also delivered approximately 50% more total pterostilbene into the blood than pTeroPure® delivered alone, thus potentially enhancing the functional benefits of pterostilbene. Pterostilbene is a highly bioavailable analog of resveratrol—a stilbenoid found in blueberries and grapes. Compared to resveratrol, pterostilbene is four times more bioavailable, has a seven times greater half-life, exhibits greater oral absorption and metabolic stability (pterostilbene is more lipophilic), and produces two to four times greater cellular uptake. Aside from resveratrol’s well-known antioxidant benefits that support cardiovascular health, pterostilbene is also known to activate certain proteins (i.e., SIRT1 and PGC-1α) involved in increasing mitochondrial biogenesis and therefore ATP (energy) production.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eElectrolytes and Antioxidants \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eElectrolytes—including sodium, potassium, and magnesium— are important for energy production, nerve transmission, muscle contractions, pH balance, fluid balance, and more. Conditions that promote excessive sweating and increased metabolic activity can require replacement of these important minerals and increase the need for antioxidants. Great Workout provides 130 mg of sodium, 280 mg of potassium, and 150 mg of magnesium in each serving. To support protection from free radicals, Great Workout provides 500 mg of vitamin C in the form of four mineral ascorbates, as well as natural vitamin E, selenium, green tea extract, and s-acetyl-L-glutathione (SAG). SAG is an orally stable glutathione that has been shown to cross the membrane of the mitochondria, which increases the organelle’s activity and helps minimize reactive oxygen species.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHerbs and Amino Acids \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eGreat Workout combines Purenergy in a proprietary blend with various herbs and amino acids, including green tea extract, coffee fruit extract, taurine, and L-arginine alpha-ketoglutarate. This proprietary blend is designed to complement the activities of Purenergy. Furthermore, some of these individual ingredients taken in high doses have roles in mitochondrial biogenesis or are known to have a positive influence on exercise performance.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eB Vitamins \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eAs essential parts of coenzymes, these water-soluble nutrients are integral to the complex biochemical processes that convert food to glucose and ATP—the energy used by cells. Vitamin B12 also works closely with folate to help make red blood cells and facilitate the work of iron in the body. Iron helps carry oxygen to all cells, including muscle cells, for use in the generation of energy.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDirections: \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eDissolve the contents of one stick pack in 6-12oz of water according to preferred sweetness. Consume the effervescent drink once daily or use as directed by your healthcare practitioner.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740315201784,"sku":"90c312d7fc98","price":55.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2264132803.jpg?v=1780291477"},{"product_id":"gut-defend-probiotic","title":"Gut Defend Probiotic","description":"\u003cp\u003eThe GI tract is a finely balanced environment where roughly 500 different strains of bacteria compete for space and nutrients.\u003c\/p\u003e\u003cp\u003eWhen there is a healthy balance (eubiosis), few symptoms exist. However, dysbiosis can occur when an overabundance of potentially harmful organisms prevail. The natural microflora balance can be upset by medications (such as antibiotics, oral contraceptives, etc.), excessive alcohol consumption, or poor\u003c\/p\u003e\u003cp\u003edietary intake.\u003c\/p\u003e\u003cp\u003eProbiotics have been extensively studied and are characterized as having broad GI and immune benefits, including (1) increasing the population of healthy bacteria following microflora imbalance; (2) supporting healthy bowel function; (3) increasing the production of short-chain fatty acids, which provide energy to the cells of the intestinal lining; (4) strengthening the gut-immune barrier by promoting a healthy gut mucosa; (5) aiding in the digestion of difficult-to-breakdown like lactose and casein; and (6) enhancing detoxification of harmful compounds.\u003c\/p\u003e\u003cp\u003eBecause probiotics are live organisms, there are many challenges associated with manufacturing and distributing\u003c\/p\u003e\u003cp\u003eprobiotic supplements. For a probiotic to be effective, it must be shelf-stable through the expiration date and preciselydelivered to the intestinal tract, where it can have maximum benefit. BioShield® technology is an innovative manufacturing process developed to ensure consistent and reliable results. The microorganisms in this product are protected, sealed and freeze dried away from moisture, heat, light and oxygen. This allows the bacteria to remain dormant until they are exposed to moisture in the GI tract. By utilizing advanced encapsulation\u003c\/p\u003e\u003cp\u003etechnology, the probiotic organisms are preserved and released on-target for maximum benefit.\u003c\/p\u003e\u003cp\u003eLactobacillus acidophilus (La-14)†\u003c\/p\u003e\u003cp\u003eLactobacillus acidophilus is a beneficial bacterial strain that is normally found in the intestinal tract and mouth and is commercially used in dairy products for the production of acidophilus-type yogurt. L. acidophilus ferments various carbohydrates to produce lactic acid, which increases the absorption and bioavailability of minerals. This includes calcium, copper, magnesium and manganese. The production of lactic acid also promotes health by creating an inhospitable environment for invading microbes.1 L. acidophilus has been shown to protect intestinal cells by competing for adhesion space in the gut against harmful bacteria, such as E. coli. The L. acidophilus strain in this product has been specifically chosen because of its strong adherence and survival attributes in the GI tract. It has been demonstrated in vitro to tolerate exposure to gastric acid and bile salts, and has the ability to withstand antibiotics including Ciproflaxin, Polymyxin B and Tetracycline.2\u003c\/p\u003e\u003cp\u003eLactobacillus paracasei (Lpc-37)†\u003c\/p\u003e\u003cp\u003eLactobacillus paracasei has been shown to protect against the harmful effects of bacteria such as Staphylococcus aureus (S. aureus).3 L. paracasei colonizes the intestinal tract by reinforcing defense mechanisms that support an immune response. It does this by supporting T-helper cell production and secreting secretory IgA (sIgA), an antibody critical for supporting intestinal immunity.4 L. paracasei Lpc-37 is a gastric acid-resistant strain and has been shown in vitro to withstand antibiotics such as Ciproflaxin and Vancomycin.5\u003c\/p\u003e\u003cp\u003eBifidobacterium bifidum (Bb-02)†\u003c\/p\u003e\u003cp\u003eBifidobacterium bifidum has been shown to effectively compete with harmful bacteria such as E. coli, S. aureus and\u003c\/p\u003e\u003cp\u003eCamplylobacter jejuni, which suggests B. bifidum’s lactic acid and acetic acid production provides an antagonistic action against pathogens to help maintain microflora balance.6\u003c\/p\u003e\u003cp\u003eBifidobacterium lactis (BI-04)†\u003c\/p\u003e\u003cp\u003eBifidobacterium lactis is predominantly found in the colon. A double-blind, randomized placebo-controlled trial on subjects receiving B. lactis or placebo for eight weeks found that B. lactis supported a balanced immune response in individuals hypersensitive to environmental allergens.7 Studies examining immune development and dietary supplementation with B. lactis have shown that it supports GI health by reducing\u003c\/p\u003e\u003cp\u003eintestinal permeability.8\u003c\/p\u003e\u003cp\u003eLactobacillus plantarum (Lp-115)†\u003c\/p\u003e\u003cp\u003eLactobacillus plantarum is a beneficial bacteria commonly found in fermented foods including sauerkraut, pickles,\u003c\/p\u003e\u003cp\u003ebrined olives and sourdough. L. plantarum has been found to compete against strains of Clostridium difficile and Clostridium perfringens, due to the production of bacteriocins (lethal proteins) that inhibit bacterial growth.9 Studies have also demonstrated that L. plantarum helps boost the immune response by stimulating Th1-mediated immunity.10\u003c\/p\u003e\u003cp\u003eLactobacillus rhamnosus (Lr-32)†\u003c\/p\u003e\u003cp\u003eLactobacillus rhamnosus has been proven to have remarkable survivability in the acid and bile environments in the GI tract. L. rhamnosus is particularly useful because of its ability to adhere to cells, enhance microflora balance, and inhibit pathogen adherence. L. rhamnosus was also found to positively affect inflammatory and immune gene signaling of over 1,700 genes when administered in high doses.11\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCaution \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eIf you are pregnant or nursing, consult your physician\u003c\/p\u003e\u003cp\u003ebefore taking this product.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740315234552,"sku":"6","price":102.0,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/853435359.jpg?v=1780291479"},{"product_id":"gut-health-cleanse-wormwood-olive-leaf-extract-and-berberine","title":"Gut Health Cleanse Wormwood, Olive Leaf Extract and Berberine","description":"\u003cp\u003eFormulated with the goal of supporting the gastrointestinal (GI) flora by promoting balanced immunity, the plant compounds in this product also provide potent antioxidant support, to help fend off microbial challenges. The ingredients in This product help to maintain a healthy GI environment by supplying botanicals shown to create a hostile environment for pathogenic microbes. Each capsule of this product includes sweet wormwood (150 mg), olive leaf extract (100 mg), black walnut hulls (85 mg) and artemisinin (25 mg).\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOverview:\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eOverview Gastrointestinal health is directly affected by factors, such as exposure to microbes, poor diet and a stressful lifestyle, that can negatively impact immune function. The prevalence of refined sugars and carbohydrates and the low presence of fiber in the modern diet has been directly linked to the alteration of the colonic environment.1 Since the body’s immune system is a complex and dynamic defense system, healthy microbial balance and antioxidant support help ensure more optimal immune function. Maintaining healthy microbial balance is not only integral to optimal GI health, but also supports overall health and well-being. This product provides a blend of plant compounds which work together to defend against microbial stressors. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWormwood\/Artemisinin\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eWormwood is a fern-like plant commonly found throughout Asia, and artemisinin is its active constituent. Artemisinin is a sesquiterpene lactone, a special compound shown to have strong microbial-balancing properties. It is known to interfere with microbial metabolism by causing structural changes to unfriendly organisms that prevent them from maturing in the body. This effect is facilitated by the production of free radicals and reactive aldehydes within the microbes that disrupt their growth.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOlive Leaf Extract\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eWidely consumed in the Mediterranean, olives contain numerous phenolic compounds, including oleuropein, which have demonstrated broad spectrum microbial-balancing and antioxidant properties. Oleuropein is a unique polyphenol molecule in olive leaf extract and special processing techniques now allow for the extraction of a stable, standardized form of oleuropein. Oleuropein is a potent antioxidant, supports microbial balance, and helps maintain a healthy cycle of inflammation in the body. Studies have indicated that oleuropein boosts host immune defense and it is especially helpful in supporting those with microbial challenges related to microbial imbalances in the intestines. In one in vitro study, phenolic compounds from olive leaf, including oleuropein, were able to interfere the cellular metabolism of a wide range of microbes creating a hostile environment to their survival. Another study found olive leaf extract prevents cell-to-cell attachment in a dose-dependent manner, a key mechanism in supporting healthy microbial balance.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBlack Walnut†\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe hulls of the black walnut have been used since Greek and Roman times to support those with intestinal complaints. Black walnut has compounds known as tannins, which affect the structural stability of various microbes. The activity (minimum inhibitory concentration) of four different tannin containing plants was determined by broth dilution method, and black walnut was found to be the most active against various microbes.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBerberine Sulfate\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eBerberine is an alkaloid extracted from plant roots that is commonly found in barberry, turmeric and Oregon grape. Berberine extracts have shown significant ability to influence the activity of a variety of organisms that affect human health. In vitro, berberine has been found to promote GI health10 and, among 25 patients, 5 mg\/kg per day of berberine for six days promoted positive changes in the microbial samples of 17 patients. Mechanisms of action for berberine include effects on organism adhesion and intracellular interference, metabolic activity, maturation and free radical formation. By addressing the intestinal secretion of water and electrolytes induced by certain organism toxins, berberine also supports the healthy formation of stool. In this way, it promotes healthy intestinal motility and normal intestinal transit time. Both in vitro and animal research suggest berberine can also affect COX-2 protein, promoting a balanced cycle of inflammation.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e Directions\u003c\/strong\u003e 1 capsule three times per day or as recommended by your health care professional.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740315267320,"sku":"f34481335bef","price":94.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2253572088.jpg?v=1780291480"},{"product_id":"histfx-vitamin-c-quercetin-and-stinging-nettles-leaf","title":"HistFx Vitamin C, Quercetin and Stinging Nettles Leaf","description":"\u003cp\u003eThis product is a targeted blend of flavonoids, antioxidants, proteolytic enzymes and botanicals designed to provide comprehensive support for seasonal challenges caused by common environmental allergens. Natural D- Hist includes quercetin, a powerful flavonoid, to support healthy histamine levels. Bromelain enhances the absorption of quercetin and supports mucosal tissue health. Stinging nettles leaf balance hyper-immune response and N-acetyl cysteine clear the airways by promoting normal viscosity of mucus. This powerful combination actively promotes healthy nasal and sinus passages for individuals with elevated histamine and respiratory irritation. Also available in convenient blister packs.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOverview: \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eQuercetin\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eQuercetin is a biologically active flavonoid antioxidant that is widely distributed in plants including oak trees, onions and tea. Quercetin has strong antioxidant activity and has been shown to support immune health by mediating the release of inflammatory compounds including leukotrienes and prostaglandins. Quercetin is known for its ability to stabilize mast cells, diminishing the release of histamine, the compound known to cause hypersensitivity reactions during seasonal changes. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eStinging Nettles Leaf\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eUrtica dioica, commonly known as stinging nettles, is a plant that has been shown to balance immune response, specifically in the airways and nasal passages. Studies have shown that the extract of stinging nettles leaf balances a variety of inflammatory activities that affect respiratory health. Stinging nettles leaf controls mast-cell degranulation, prostaglandin formation, and histamine action all contributing to a balanced inflammatory response. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBromelain\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eBromelain is a plant enzyme naturally found on the stem and fruit of the pineapple plant. Bromelain is a proteolytic enzyme that aids in in the breakdown of large protein complexes, including antigenic compounds, and has been shown to enhance the absorption of quercetin. Bromelain has been shown to reduce circulating allergenic protein complexes associated with hyper-immune sensitivity and seasonal discomfort.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eN-Acetyl Cysteine\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eN-acetyl cysteine (NAC) is an amino acid precursor to one of the most important antioxidants in the body, glutathione. Both glutathione and NAC help reduce the viscosity of the mucus allowing for clearing of the airways and improved respiratory health. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eVitamin C\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eVitamin C cannot be synthesized by humans and is therefore an essential nutrient that must be consumed in the diet. Among its numerous health-promoting properties, vitamin C is an essential vitamin that supports the immune system and is also a potent antioxidant. When the body is under a significant amount of stress, both emotional and environmental, vitamin C is excreted rapidly. Vitamin C has many immune boosting properties, but is distinctively beneficial for individuals with seasonal discomfort because of its ability to deactivate histamine. \u003c\/p\u003e\u003cp\u003eDirections: \u003c\/p\u003e\u003cp\u003eLoading Dose: 2 capsules three times per day for 7-10 days or as recommended by your health care professional. \u003c\/p\u003e\u003cp\u003eMaintenance: 2 or more capsules per day or as recommended by health care professional.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740315300088,"sku":"5d1627c9aeac","price":92.4,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2253570679.jpg?v=1780291481"},{"product_id":"hyperimmune-egg-pro-ig-26","title":"HyperImmune Egg Pro-IG 26","description":"\u003cp\u003eHyper Immune Egg is a self-affirmed GRAS supplements that provides IgY immunoglobulins and immunoregulating molecules from hyperimmune chicken egg. Research suggests that this dairy-free source of immunoglobulins and immune cofactors helps support immune function in the intestine and a healthy intestinal environment. These benefits positively impact extraintestinal health. Preliminary research also suggests the immunoregulating molecules in this formula help modulate cytokines and enhance sports recovery.\u003c\/p\u003e\u003cp\u003eHyper Immune Egg is a self-affirmed GRAS supplements that provides IgY immunoglobulins and immunoregulating molecules from hyperimmune chicken egg. Research suggests that this dairy-free source of immunoglobulins and immune cofactors helps support immune function in the intestine and a healthy intestinal environment. These benefits positively impact extra-intestinal health. Preliminary research also suggests the immunoregulating molecules in this formula help modulate cytokines and enhance sports recovery.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOverview: \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eDecades ago, immunology researchers began investigating the possible health benefits to humans that could be achieved by the consumption of products from hyperimmunized lactating cows and laying hens. Agricultural scientists soon discovered that they could simultaneously immunize a single laying hen against multiple human germs. The resulting avian immunoglobulins, known as IgY, are transferred to the egg yolk, paralleling the way human immunoglobulins (IgG) are passed to the placenta. From this discovery, a new functional food was born: the “hyperimmune egg.” Hyper Immune Egg is the result of special hyperimmune egg harvesting and processing techniques that result in a polyvalent, immunoglobulin-rich, dried hyperimmune egg food product that can be consumed as a dietary supplement. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eIgY Immunoglobulins and Passive Immunity\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eHyperimmune egg provides a concentrated source of environmentally specific IgY antibodies and immune-supporting cofactors that can confer passive immunity to the human being who consumes it. There are over 100 patents associated with the production of hyperimmune egg and its use in animals and humans, and it is a self-affirmed GRAS (generally recognized as safe) product—a designation that affirms safe consumption. Furthermore, hyperimmune egg and IgY have been studied extensively. Oral Health In a study of healthy volunteers, the use of an oral rinse containing an aqueous IgY solution increased the presence of active antibodies in saliva. Moreover, in vitro, animal, and human research support the benefits of custom IgY solutions, IgY-supplemented diets, and IgY-containing pastes that are designed for use in the dental plaque environment and to promote gingival health. Intestinal Health IgY stability through the orogastrointestinal tract and its safety profile are well-documented. In vitro, animal, and human studies provide evidence that supplemental IgY from hyperimmune egg imparts passive immunity in the intestinal tract. Providing the body with an increased supply of immunoglobulins also helps maintain a healthy balance of bacteria in the intestine. Supporting passive immunity and promoting microbiome balance lead to better overall health due to the link between gut health and systemic health. Furthermore, researchers postulate that by supporting passive immunity in the gut, immune over activation might be reduced.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eImmunoregulatory Factors\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eHyperimmune egg not only provides IgY immunoglobulins, but it also contains bioactive immunoregulatory factors. These immunoregulatory factors act directly on gastrointestinal surfaces where they may influence effector cells and also circulate systemically where they act as intercellular communicators. As intercellular communicators, they are responsible for the regulation of a variety of immune, hormonal, and metabolic pathways that have widespread systemic effects. Preliminary studies suggest that these immunoregulatory factors in Hyper Immune Egg benefit cytokine modulation, joint health, blood lipid metabolism, exercise performance, and overall wellness. FiberAid, in doses of 4.5 g and higher, has been demonstrated to increase gut anaerobes such as lactobacilli and bifidobacteria, increase shortchain fatty acids, reduce ammonia levels in the large intestine, and support immunomodulatory activity. Cytokine Modulation Hyperimmune egg contains heightened levels of cytokine inhibitory factor (CIF) and cytokine activating factor (CAF). These bioactive molecules help balance the production of cytokines such as TNF-alpha and are believed to help the immune system recognize when to turn on and when to turn off. Muscle Performance and Recovery In clinical studies comparing the benefits of hyperimmune egg to an egg-protein placebo group, oral supplementation of hyperimmune egg (4.5 g to 13.5 g) for 10 days resulted in a significantly lower submaximal heart rate and higher peak power. [20] In a double-blind, balanced, matched-pairs study, oral supplementation of hyperimmune egg (4.5 g to 13.5 g) improved strength performance and enhanced muscle recovery. The supplemented group also experienced significantly less muscle soreness. Other studies suggested that hyperimmune egg significantly increased levels of growth factors and overall bioavailability of IGF-1. Quality of Life HIV\/AIDS patients with varying levels of sickness were administered hyperimmune egg (4.5 g) for four to eight weeks. Research showed that supplementation appeared to improve multiple parameters of physical and mental well-being. Cardiovascular and Joint Health Studies have indicated that the consumption of hyperimmune egg may also support cardiovascular and joint health.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740315595000,"sku":"5241f7f3ee61","price":75.75,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2264089475.jpg?v=1780291483"},{"product_id":"immune-support-astragalus-root-elderberry-and-echinacea","title":"Immune Support Astragalus Root, Elderberry and Echinacea","description":"\u003cp\u003eOur body’s immune system is a complex and dynamic defense system that comes to our rescue at the first sign of exposure to an outside invader. The dynamic nature of the immune system means that all factors that affect health need to be addressed in order for it to function at peak performance. The immune system is very sensitive to nutrient deficiencies. While vitamin deficiencies can compromise the immune system, consuming immune enhancing nutrients and botanicals can support and strengthen your body’s immune response. This product’s synergistic formula significantly boosts immune cell function including antibody response, natural killer (NK) cell activity, thymus hormone secretions, and T-cell activation. This product also helps soothe throat irritations and nasal secretions, and promotes healthy inflammatory balance by increasing antioxidant levels throughout the body. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eImmune Nutrition Base\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThis product contains the synergistic nutrient blend of zinc, vitamin C, vitamin A, L-lysine and pantothenic acid which each play a major role in maintaining a healthy, functioning immune system. Zinc† Zinc is a mineral that works synergistically with vitamin A in activating thymic factor, a thymus hormone with vital immune supporting properties. Maintaining optimal zinc levels also helps maintain helper T-cell lymphocyte function, NK cell activity, macrophage function, and antibody production. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eVitamin C \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eVitamin C is well known for its ability to support immune response. Vitamin C concentrations decline rapidly in the body during periods of stress. Dietary intake is therefore crucial during immune challenges. Vitamin C has been found to be helpful in supporting specific components of the immune system including NK cell activity and lymphocyte function. Vitamin C also provides antioxidant support by protecting cells against reactive oxygen species that are generated during normal inflammatory response. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eVitamin A \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eVitamin A helps support mucous membranes. When vitamin A is lacking, mucus-producing cells are replaced by keratin producing cells, and the membranes become tough and more vulnerable to organisms. Vitamin A is a critical immune supporting nutrient. Vitamin A also supports the immune system by stimulating white blood cell function and increasing antibody response. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eL-Lysine\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eL-lysine is an essential amino acid that cannot be synthesized in the body on its own. Lysine must be derived from protein sources in the diet in order for the body to function properly. Many biological functions require lysine including boosting immune defense. A study conducted in China examined the immunological effects of lysine. Of eighty-eight families included in the study, half received wheat flour fortified with 3 g of lysine per kilogram of flour, the other half received wheat flour without fortification. Those given the fortified flour showed improved immune function, versus the placebo group, specifically showing an increase of CD3 T-cells, IgG, IgA, and IgM. Pantothenic Acid (vitamin B5) Pantothenic acid (vitamin B5) is a water-soluble B complex vitamin. D-calcium pantothenate is a heat stable form of B5. About 85% of pantothenic acid in food occurs as a component of coenzyme A (CoA). As a component of CoA, pantothenic acid is essential for the production of energy from carbohydrates, fats and protein. Maintaining optimal pantothenic acid levels is crucial for supporting immune system energy, thymic function and healthy white blood cell levels. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBlack elderberry Extract\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eBlack elderberry (Sambucas nigra) has a long history of traditional use among herbalists and is native to Europe, Northern Africa, and Western and Central Asia. Elderberry preparations range from expressed juice to syrup, tea decoction, powdered extract, and powdered extract in the form of lozenges or capsules. The bioactive components of elderberry include the flavonoid anthocyanin. This product is standardized to include black elderberry extract with 13% anthocyanins. Black elderberry preparations have also been shown to enhance immune cell killing potential by supporting healthy cytokine production, including IL-8 and IL-10, the cellular pathways used to eliminate foreign invaders. Astragalus Membranaceus Root Extract† Astragalus membranaceus is native to northern China and has been traditionally used to strengthen the immune system. The root of A. membranaceus is one of the two commonly used species in traditional Chinese medicine. Research has demonstrated the immune-regulating effects of astragalus which include boosting T-dependent antigens, and lymphokine-activated killer (LAK) cells and macrophage activity. Additional studies have demonstrated that A. membranaceus root extract supports immune response by boosting T3, T4and T4\/T8 cell ratios. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eEchinacea Purpurea Extract\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eEchinacea purpurea is a perennial herb that has been used for centuries in Native American medicine. Current research has supported echinacea’s clinical applications as this botanical has been the subject of more than 300 scientific studies. Echinacea activates multiple aspects of immune function including enhancing leukocyte and granulocyte counts, activating neutrophils, monocytes, and eosinophils and solubilizing immune complexes. Echinacea has been shown to compete with pathogens by blocking viral receptors on cell surfaces. Echinacea also diminishes hyaluronidase, a compound which increases connective tissue permeability and allows pathogenic organisms to become more invasive. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAndrographis Paniculata Leaf Extract\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eAndrographis paniculata is a plant that has been used in Asian medicine for centuries. Traditionally, the plant has been used as an infusion, decoction or powder, either alone or in combination with other herbal plants. In a study examining 158 patients, a standardized preparation of A. paniculata dried extract administered for five days significantly supported immune response while decreasing throat irritations and nasal secretions. An additional study examining the effects of A. paniculata found that andrographolide administration significantly improved CD4+ lymphocyte count in patients which immune challenges. A. paniculata has also been reported to provide strong antioxidant support due to its ability to activate highly protective antioxidant reactions including superoxide dismutase, catalase and glutathione-S-transferase. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDirections\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e For immediate immune support: 1-2 capsules per hour or as recommended by your health care professional. For immune maintenance: 2 capsules per day or as recommended by your health care professional.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740316315896,"sku":"a127c284c553","price":73.2,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2253535394.jpg?v=1780291484"},{"product_id":"joint-performance-iv-msm-green-lipped-mussel-and-vitamin-c","title":"Joint Performance IV MSM, Green-Lipped Mussel and Vitamin C","description":"\u003cp\u003eYears of joint tissue stress, underlying cytokine imbalance, and other factors can upset the equilibrium between anabolic and catabolic processes in the joints. The cooperative ingredients in Joint Performance IV nourish joint tissues and help support balanced metabolic activity within them.\u003c\/p\u003e\u003cp\u003eGreen-Lipped Mussel (GLM) (Perna canaliculus) Causenta®’s GLMs are sourced from unpolluted waters off New Zealand and are guaranteed to be pure. They contain glycosaminoglycans (GAGs)—the principal components of cartilage and synovial fluid—as well as eicosatetraenoic acid, which promotes a healthy joint environment. GLMs have been shown to inhibit cyclooxygenase and lipoxygenase enzymes. Results of a systematic review of human randomized or placebo-controlled trials show that GLM supplementation (900-1200 mg\/d) helps maintain healthy joint tissue and function.\u003c\/p\u003e\u003cp\u003eHyal-Joint® Hyaluronic acid (HA) is responsible for the viscoelastic and lubricating properties of synovial fluid as well as for performing biophysical, biochemical, and cell-regulatory roles in joint synovial tissues. Given these critical tasks, HA has become a focus of proactive joint care. Hyal-Joint is a proprietary rooster comb extract rich in high-molecular–weight HA; it also contains collagen and other GAGs.\u003c\/p\u003e\u003cp\u003eResearch suggests that Hyal-Joint supports the quality of synovial fluid by positively influencing synovial HA concentration and by reducing the expression of degradative factors in synovial fluid.[4-8] Furthermore, scientific evidence shows that Hyal-Joint is two to four times more active than regular HA in nourishing and supporting the health of synovial fluid.This higher degree of activity comes from the unique composition of Hyal-Joint, which naturally contains key ingredients that benefit synovial fluid.\u003c\/p\u003e\u003cp\u003eCS BiO-ACTIVE® Chondroitin sulfate (CS) is a GAG required for the formation of proteoglycans found in joint cartilage. CS is thought to enhance joint health by supporting endogenous synthesis and preventing degradation of other joint GAGs. Oral administration of CS (800- 200 mg\/d) has proven to positively influence joint space width, joint comfort, and fluid accumulation. The pharmaceutical grade, low molecular–weight CS in CS BiO-ACTIVE has demonstrated higher bioavailability and greater biological activity than other CS sources.\u003c\/p\u003e\u003cp\u003eCS BiO-ACTIVE is the reference CS for the European Union Pharmacopoeia, and it was selected by the US National Institutes of Health for their glucosamine\/chondroitin trial. In fact, most of the clinical research performed using CS has employed CS BiO-ACTIVE; and in all clinical trials and over 10 years of pharmacovigilance, CS BiO-ACTIVE has shown an excellent safety profile.\u003c\/p\u003e\u003cp\u003eGlucosamine Sulfate Glucosamine is an amino saccharide that research suggests stimulates chondrocytes, supports GAG synthesis, incorporates sulfur into cartilage, induces HA production, and modulates prostaglandin (e.g., PGE2) synthesis. Most of the scientific research done on glucosamine has been performed using glucosamine sulfate. Oral doses of 1,500 mg\/d show clinical benefits in joint mobility and comfort. It is postulated that lower doses may nourish the joint tissues, especially in combination with chondroitin sulfate.\u003c\/p\u003e\u003cp\u003eSeveral studies confirm that the benefits of combining glucosamine sulfate and chondroitin sulfate outweigh taking them alone.\u003c\/p\u003e\u003cp\u003eMethylsulfonylmethane (MSM) As an organosulfur compound, MSM is thought to primarily benefit joint tissues by delivering sulfur.\u003c\/p\u003e\u003cp\u003eSulfur helps maintain the strength and structure of connective tissue by forming cross-linkages through disulfide bonds—such as those found in GAGs. Research suggests that MSM may reduce joint tissue damage triggered by free radicals. One joint study shows that glucosamine and MSM achieve better results when combined than when administered individually.\u003c\/p\u003e\u003cp\u003eVitamin C and Manganese Vitamin C is essential to the synthesis of collagen and to the maintenance of collagen integrity. Furthermore, an animal study suggests that serum ascorbate levels influence fluid accumulation in the joint. Manganese assists the growth and development of normal bone and the synthesis of cartilage. Pairing manganese with chondroitin and glucosamine in high doses has yielded positive effects on joints, and one combination study demonstrated a synergistic protective effect on joints.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740317298936,"sku":"808ae3019de1","price":98.4,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2264112423.jpg?v=1780291487"},{"product_id":"mood-pro-ii-taurine-l-theanine-gaba-and-5-htp","title":"Mood Pro II Taurine, L-Theanine, GABA and 5-HTP","description":"\u003cp\u003eNeurotransmitters are the chemical messengers that regulate mood, memory, sleep cycle and daily stress. Adequate neurotransmitter production depends on an adequate supply of amino acids, vitamins and minerals in the diet. High levels of stress, dietary deficiencies, genetics, medications and toxins all play a role in neurotransmitter depletion. The nutrients in this product support healthy levels of serotonin and GABA, the brain’s primary neurotransmitters for balancing the stress response. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eL-Theanine\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eL-theanine is an amino acid found abundantly in green tea. L-theanine has been shown to quickly improve stress perception and resilience. The stress-buffering mechanisms of L-theanine have been connected its ability to increase serotonin and dopamine production in the brain. L-theanine has also been shown to significantly increase alpha brain wave activity, which is critical for increasing attention as well as promoting a sense of relaxation. In a study on healthy volunteers, electroencephalograph (EEG) readings of participants were recorded following the ingestion of 50 mg of L-theanine. The researchers found a greater increase in alpha brain wave activity versus placebo. L-theanine has also been shown to have a protective effect on nerve cells overstimulated by the excitatory neurotransmitter glutamate. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePharmaGABATM\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eGamma-amino butyric acid (GABA) is one of the major inhibitory neurotransmitters in the brain. GABA provides a calming effect and is a primary component of the body’s stress fighting mechanisms. GABA is also available as a dietary supplement. Most commercially available forms of GABA utilize synthetically-produced GABA, manufactured from pyrrolidinone, a compound not allowed for use in Japan. This product includes a patented, naturally-sourced, non-synthetic form of GABA called PharmaGABATM. It is produced naturally by the friendly bacteria, Lactobacillus hilgardii. In contrast to synthetic GABA sources, PharmaGABATM has been shown in published research studies to promote relaxation effects in the central nervous system (CNS). In a double-blind study using healthy volunteers, EEG readings were obtained after 100 mg of PharmaGABATM was administered. PharmaGABATM produced a highly significant increase in alpha waves, as well as a significant decrease in beta waves, when compared to the control group. Alpha brain waves are associated with relaxed and effortless focus, while beta waves are associated with stress, restlessness and scattered thoughts. Therefore, an increase in alpha to beta waves is associated with improved concentration and a state of centered relaxation. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eInositol\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eInositol is a B vitamin that is an important component of cell membrane signaling. As part of the cellular signaling system of the CNS, inositol is crucial for the release of neurotransmitters from within the nerve cells. A deficiency of inositol can affect brain signaling, resulting in inadequate neurotransmitter release causing irritability, worry and restlessness.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTaurine\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eTaurine is an amino acid that is found abundantly in the brain and has neuroprotective properties. Taurine promotes inhibitory neurotransmission due to its ability to activate GABA receptors. Taurine also supports inhibitory neurotransmission by activating glycine receptors in the brain.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e5-HTP\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e5-hydroxytryptophan (5-HTP) is an amino acid intermediate that is directly converted into the mood-regulating neurotransmitter serotonin. Maintaining a healthy serotonin level is important for regulating appetite and sleep cycle and for supporting a sense of calmness. As a dietary supplement, 5-HTP is produced naturally from the seeds of the African plant, Griffonia simplifolia. In contrast to L-tryptophan, 5-HTP provides efficient conversion into serotonin because it does not need prior conversion by tryptophan hydroxylase.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eMicronutrients\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThis product includes essential nutrients that are required for the synthesis of serotonin and GABA neurotransmitters. This includes 5-methyltetrahydrofolate (5-MTHF), vitamin B6 (P-5-P), vitamin C, zinc and magnesium. 5-MTHF is the biologically active form of the B vitamin folic acid, which is vital for supporting proper mood regulation. 5-MTHF works together with B12 as a methyl group donor. Methyl (CH3 ) group donation is important for maintaining neurotransmitter synthesis. Magnesium is a mineral that calms the nervous system by binding to glutamate receptors, which reduces excitatory neurotransmitter activity. The combination of the minerals zinc and magnesium helps reduce glutamate to nontoxic levels, providing significant neuroprotection.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDirections \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e3 capsules taken 1-3 times per day or as recommended by your health care professional.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740317331704,"sku":"b9fc8e4f7a76","price":114.3,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2253552330.jpg?v=1780291488"},{"product_id":"muscle-aminos-bcaas","title":"Muscle Aminos - BCAAs","description":"\u003cp\u003eThe amino acid (AA) formula that comprises Muscle Aminos was meticulously developed and studied by internationally recognized researchers in the fields of muscle metabolism and aging and longevity. Seventeen years of research have resulted in this particular blend of the nine essential amino acids (EAAs)— including the branched-chain amino acids leucine, isoleucine, and valine—plus arginine, proportioned in the most optimal ratios for muscle anabolism. Muscle Aminos is designed for both young and elderly individuals who are seeking to stimulate muscle protein synthesis, hasten muscle recovery, and promote muscle strength and function.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eQuality Not Quantity \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eAmino acids are potent stimulators of muscle protein synthesis in both the young and the elderly. Of the AAs, data indicate that EAAs are primarily responsible for this biological process. Moreover, studies demonstrate that there is no additional benefit to muscle protein synthesis from adding nonessential AAs to an EAA supplement. For instance, the addition of 22 g of non-essential AAs to 18 g of EAAs produced no additional benefit to net muscle balance when compared to the provision of 18 g of EAAs alone. Likewise, a 15 g EAA supplement—with the nine EAAs in similar ratios to Muscle Aminos—had twice the impact on muscle protein synthesis than that of an equal amount (15 g) of a high-quality protein.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWhy Include Arginine?\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e In healthy young adults, sufficient arginine can be synthesized to meet normal demands. However, during rapid growth or in response to stress, there are heightened needs for arginine that may not be fully met. Furthermore, there is evidence that arginine has a unique stimulatory effect on muscle protein synthesis. While all mechanisms have not been fully elucidated and are likely multifactorial, it is known that arginine converts to nitric oxide, which relaxes blood vessels and improves blood flow to muscles. Last, arginine availability influences its own catabolism and that of other amino acids by controlling ureagenesis. A critical finding that solidified the need to add arginine to the EAA formulation was that without it, plasma arginine decreases; therefore, the rate of protein synthesis is potentially reduced.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eEssential Amino Acids and Exercise \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe effectiveness of EAA intake is amplified by ingestion before exercise because of the increased delivery of amino acids to the muscles. In fact, results from acute studies have shown that exercise and EAA intake have additive effects on muscle protein synthesis. Furthermore, branchedchain AAs (BCAAs), have been demonstrated to hasten post-exercise muscle recovery. Data show that BCAA (e.g., leucine) supplementation before and after exercise helps decrease exercise-induced muscle damage, promotes muscle protein synthesis, and modulates exercise-related cytokine production. For example, leucine-enriched EAA supplementation (total EAA was 10 g of which 1.85 g were leucine) prolonged the anabolic response and the sensitivity of skeletal muscle to AAs. Børsheim et al propose that over time, exercise will increase the beneficial effects of EAA supplementation on lean body mass and strength and improve functional parameters of muscles.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eMuscle Loss with Aging \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eBeginning in the fourth decade of life, there is a natural and gradual decline in muscle mass (catabolism), strength, and function as a result of the innate metabolic changes and the more sedentary lifestyle that accompany aging. Studies using EAA supplementation at doses of 6.7 to 45 g\/d in advanced age, bed rest, and recovery from surgery have demonstrated important benefits. These benefits include stimulation of muscle protein synthesis, enhancements in muscle strength, and improvements in functional parameters of the studied muscle(s).\u003c\/p\u003e\u003cp\u003eIn the Elderly Protein supplements are often used to help ward off muscle-related losses in the elderly. According to Ferrando et al, “Increasing protein intake to 1.4 g\/kg\/d in the elderly with EAA supplementation indicates the potential for preserving muscle function.” Because non-essential AAs are not as effective as EAAs for muscle anabolism, supplements containing significant calories in the form of non-essential AAs may be inadequate to maximize anabolic efficiency in the elderly.[9] Furthermore, the elderly tend to use protein supplements as calorie substitutes and reduce their food intake. In these cases, it becomes critical that the AA supplement be low calorie, so as not to influence satiety, and highly efficient to confer maximum benefits to skeletal muscle. A high proportion of leucine is another factor that is required for optimal stimulation of muscle protein synthesis in the elderly. Additionally, there is evidence that the presence of carbohydrates in a nutritional supplement for the elderly is not beneficial and may actually impair muscle anabolism. Muscle Aminos is a highly efficient blend of EAAs plus arginine that provides zero carbohydrates.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDirections: \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eDissolve one scoop (7 g) into 8-12 oz of room-temperature water and consume once per day between meals, or use as directed by your healthcare practitioner. Consult your healthcare practitioner prior to use. Individuals taking medication should discuss potential interactions with their healthcare practitioner. Do not use if tamper seal is damaged.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740317397240,"sku":"cc8a9b99e0e2","price":49.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2264111395.jpg?v=1780291489"},{"product_id":"nac-n-acetyl-l-cysteine","title":"NAC (N-Acetyl-L-Cysteine)","description":"\u003cp\u003eN-Acetyl-L-Cysteine (NAC) is one of the few antioxidants found to raise glutathione levels. Glutathione is an important antioxidant used in many different metabolic processes within the body. Maintaining adequate levels is important to maintaining the health of the respiratory, hepatic and immune systems. It is also important in supporting antioxidant protection of lipids and proteins and supporting the normal response to inflammation. Glutathione is not well absorbed by the body when taken orally, so it can be difficult to sustain adequate glutathione levels. NAC has been shown to significantly increase glutathione levels. NAC is also capable of reducing the viscosity of mucous and is also used to support respiratory and pulmonary health. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDetox Support and Antioxidant Protection\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThough studies have shown the absorption of oral glutathione to be limited, supplementation with NAC has been shown to significantly increase circulating levels of glutathione in the body. Increasing glutathione levels in turn increases the production of specialized antioxidant enzymes such as glutathione peroxidase, glutathione reductase and detoxification enzymes such as glutathione S-transferases. Through the activity of these enzymes, NAC protects the body from oxidative damage, increases phase II detoxification, and enhances the normal breakdown of toxins and other metabolic byproducts of the body. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eRespiratory Function\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eStudies show NAC supports normal mucous production and may positively support pulmonary and respiratory function, especially when consumed over a prolonged period. A clinical trial of 100 smokers found NAC significantly improved measures of pulmonary health, and high-dose NAC taken over a one year period resulted in significantly improved small airway clarity and decreased frequency of respiratory challenges. A systematic review found NAC to be effective in supporting children’s pulmonary health as well. NAC was also shown to support pulmonary health after inhalation of mustard gas.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eNeuropsychiatry Health\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eMore recently, research has pointed to the role of NAC in targeting a diverse array of factors related to the neuropsychiatric health. NAC has been shown to protect neurons from oxidative damage, and to improve neurotransmitter production, mitochondrial function and inflammatory balance. Studies have also highlighted the role of NAC in modulating oxidative stress as its mechanism of action in neuropsychiatric health. In one 12-week, double-blind, randomized, placebo-controlled study of NAC in children with developmental delay, NAC resulted in significant improvements in irritability scores.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDirections\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e1 or more capsules per day or as recommended by your health care professional.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740317430008,"sku":"4c27038561bc","price":55.2,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2253596121.jpg?v=1780291490"},{"product_id":"niacin-500","title":"Niacin 500","description":"\u003cp\u003eThe cardiovascular benefits of niacin (vitamin B3) were introduced in the June 1956 issue of Mayo Clinic Proceedings. [1] More than 20 years later, the Framingham Heart Study touted the benefits of niacin on lipid metabolism. A decade later, as the study continued, researchers labeled niacin “front-line” cardiovascular support.[2] This status was further reinforced in 1988 when the National Cholesterol Education Program (NCEP) panel designated niacin a “first-line therapy” for support of specific parameters related to cardiovascular health.*[3] \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eMechanisms of Action \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eSeveral mechanisms of action have been proposed for niacin. Various experimental models suggest niacin can modulate lipoprotein biosynthesis in the liver, inhibit the release of free fatty acids from adipocytes, inhibit synthesis of apo B, induce lipoprotein lipase, and help maintain the structure and function of HDL (high-density lipoprotein) by reducing the amount of apo A-1 broken down from HDL during hepatic processing.[4,5] In addition, when niacin is used with resins, it can stimulate bile flow and may therefore affect lipid biosynthesis.*[6] \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHuman Trials \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eSince the late 1970s, studies and clinical trials, lasting from four weeks to five years with daily doses of extended-release (also known as sustained\/prolonged\/slow-release) niacin up to 3000 mg\/day, have consistently demonstrated niacin’s efficacy and safety.[6] In 2004, the ARBITER 6-HALTS trial clearly demonstrated that niacin offers targeted support of cardiovascular health.[7] Final results of this trial, published in 2010, further demonstrated that niacin supports healthy carotid intima-media thickness (CIMT).[8] While the supportive effect niacin has on blood lipids is well documented, there has been a recent focus by NCEP and other researchers on how niacin’s effect on HDL may influence cardiovascular events.[9] More well-designed studies that address innate limitations and are carried to completion are needed.* \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWhy Isn’t Niacin More Widely Used? \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe two common concerns are cutaneous flushing and increased liver enzymes. Cutaneous flushing is harmless, although it can be a nuisance. Flushing is most often seen with the use of immediate\/ instant-release forms of niacin and can occur with doses as low as 30 mg\/day, but it is more likely to occur with the much higher doses used to support healthy blood lipids. Flushing may last 10 to 15 minutes and rarely, but possibly, up to two hours. The proprietary wax-coated technology used in Niacin 750 tablets allows a gradual, sustained release of niacin over a seven-to-eight hour period. This delivery dramatically reduces the flushing associated with immediate-release forms. Adherence to a regimen with the special wax-coated form of niacin, as found in Niacin 750, ranged from 88-97% in four human clinical trials.[10,11] Flushing, itching, tingling, and upper gastrointestinal side effects were minimal, but did increase when dosing was increased to 2000 mg\/day. It is important to note that Niacin 750 should not be confused with “no-flush” niacin, which is inositol hexanicotinate (IHN), a supplement that does not contain any free niacin and may not be as supportive of cardiovascular health as those providing nicotinic acid.*[12,13] \u003c\/p\u003e\u003cp\u003eThe second concern with regard to liver enzyme elevation was first elucidated by the results of McKenney’s study, published in 1994 in the Journal of the American Medical Association (JAMA), wherein subjects received 3000 mg\/day of niacin over an extended period of time.[14] In April 2004, McKenney retracted his earlier warnings about the harmful effects of niacin and publicly supported its unique benefits.[15] Although they generally do not enter an unhealthy range, liver enzymes may increase when initiating niacin therapy, especially in amounts greater than 1000 mg\/day. Enzyme levels return to normal promptly after cessation of niacin.*[15] Clinical Applications Niacin is one of the most studied and documented nutrients for support of lipid levels already within the normal range, especially high-density lipoprotein cholesterol (HDL-C) levels. Sustained-release niacin, as found in Niacin 750 750, has a lesser flushing effect compared with instant-release niacin. Use of a proprietary, wax-coated technology permits release that is complete in seven to eight hours, the time that is considered ideal for a time-release form of niacin.* *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Niacin 750 mg 3750% Serving Size: 1 Tablet Servings Per Container: 60 Supplement Facts Amount Per Serving %Daily Value Other Ingredients: Vegetable waxes (rice bran and\/or carnauba), stearic acid, magnesium stearate, and silica. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDirections\u003c\/strong\u003e Take one tablet one to two times daily with food, or as directed by your healthcare practitioner\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740317462776,"sku":"726569875ce0","price":61.2,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2225792525.jpg?v=1780291491"},{"product_id":"optimum-ala-2","title":"Optimum ALA 2","description":"\u003cp\u003e\u003cstrong\u003eOptimum ALA 2\u003c\/strong\u003e is designed to help support cardiometabolic health. It delivers alpha-lipoic acid (ALA), the plant alkaloid berberine, and biotin in one convenient formula. These ingredients have been observed to support insulin activity and glucose metabolism. Research also suggests a role for berberine in supporting normal A1C levels.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740317823224,"sku":"80","price":78.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2266738802.jpg?v=1780291493"},{"product_id":"optimum-b-folate-b12-and-biotin","title":"Optimum B's Folate, B12 and Biotin","description":"\u003cp\u003eA wide and complex variety of B vitamins is essential for the body to convert food into cellular energy. These water-soluble groups of vitamins are first absorbed in the small intestine and then travel to the liver where they are biotransformed into their active coenzyme forms. One of the key roles of B vitamins is to serve as prime coenzymes for the Kreb’s cycle, the biochemical pathway responsible for maintaining energy production in the form of cellular energy. In addition, B vitamins, particularly folic acid, B6 and B12, are critical for proper methylation, a biochemical process that helps convert the problematic amino acid metabolite homocysteine into the amino acids methionine and cysteine. This process is vital for supporting cardiovascular and mental health, a healthy nervous system, regulating gene expression, proper energy metabolism, as well as immune and nerve cell function. Methylation occurs billions of times every second and helps the body to repair DNA on a continual basis. However, when methylation processes in the body slow down, an increase in the breakage of DNA strands can occur. In addition to maintaining DNA repair, methylation reactions help maintain optimal neurotransmitter production, homocysteine balance for cardiovascular health, recycle molecules that are required for detoxification and support a healthy inflammatory response. Proper methylation can be inhibited by nutrient deficiencies including folate, B2, B6 and B12. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDeficiency\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eDeficiency in any of the B vitamins can create a breakdown of metabolic processes that protect health. Many medications deplete certain B-vitamins including acetaminophen, aspirin, ibuprofen, oral contraceptives and SSRIs, along with stress and poor diet. Deficiencies of folic acid, B6 and B12 can specifically impair proper methylation, which affects many aspects of health. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFolate† \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eFolate is a water soluble member of the B complex vitamins that is critical for maintaining optimal methylation. Folate is found naturally in foods such as fruits and dark leafy vegetables, but can be easily destroyed by cooking or processing. Additionally, enzyme defects, malabsorption and congenital deficiency of 5-methylenetetrahydrofolate reductase (5-MTHFR), an enzyme required for the conversion of folic acid to its bioactive form 5-methyltetrahydrofolate (5-MTHF), can result in an impaired ability to activate folic acid. In individuals with a genetic defect of this enzyme, supplementation with 5-MTHF has been shown to be beneficial. 5-MTHF is required as a methyl group donor for the production of mood regulating neurotransmitters such as serotonin, the synthesis of melatonin, as well as DNA production and repair. 5-MTHF also donates its methyl group to vitamin B12 (cobalamin), forming methylcobalamin. Methylcobalamin helps convert the amino acid metabolite homocysteine into the amino acid methionine. Consistent recycling of homocysteine is vital to supporting cardiovascular and arterial health.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eThiamine (Vitamin B1)\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eWhile naturally abundant in whole grains, thiamine is lost in many of the over-processed grains commonly consumed today. Thiamine is an essential co-factor in the production of ATP in the cells’ Kreb’s cycle, and is also needed for the metabolism of fats, proteins and carbohydrates. A recent randomized double blind placebo-controlled trial found that supplementation with high-dose thiamine also supports blood sugar balance.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eRiboflavin (Vitamin B2)\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eRiboflavin is a precursor to flavin adenine dinucleodtide (FAD) and flavin mononucleotide (FMN), both of which are central to energy production, intermediary metabolism, and act as powerful antioxidants. Riboflavin-depleted cells have been found to display signs of greater oxidative stress and disrupted energy generation. Studies have also shown that optimal riboflavin status has been found to help maintain healthy blood pressure already within normal range in patients with certain genetic predispositions.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eNiacin\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eNiacin is a cofactor in the mitochondrial respiratory chain, which produces cellular energy. In the body, niacin is transformed into NAD (Nicotinamide adenine dinucleotide) and NADP (Nicotinamide adenine dinucleotide phosphate), which both play a role in oxidation reduction reactions in cells. Niacin or nicotinic acid has a long history of use in cardiovascular health, having been shown in numerous studies to support endothelial health.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eVitamin B6\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eVitamin B6 is involved in over 100 enzymatic reactions in the body and is essential for gluconeogenesis, lipid metabolism, neurotransmitter formation, immune health and hormone modulation, and is essential in methylation, for the breakdown of homocysteine. A large, prospective study found that women who consumed, on average, 4.6 mg of vitamin B6 daily had significantly better markers of cardiovascular health compared to women who consumed an average of 1.1 mg daily. In addition, vitamin B6 has been found to promote normal lymphocyte proliferation and interleukin-2 production in older people, both of which are important for optimal immune function.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eVitamin B12\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eVitamin B12, found only in organ meats, seafood and egg yolks, often becomes deficient in vegan and vegetarian diets. The vitamin is essential for the metabolism of fats and carbohydrates, the synthesis of proteins, and also plays a role in regulating mitochondrial enzymes and energy metabolism, as well as neurological health. In a population study of 700 women aged 65 and over, more optimal B12 levels were found to be associated with better mood balance and health.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBiotin\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eSynthesized by the bacteria in the gut in addition to certain foods, biotin and its cofactors are involved in metabolism of fatty acids, amino acids and utilization of B vitamins. Biotin has also been found to support healthy blood sugar both in animal and human studies. A randomized, double-blind placebo-controlled clinical trial conducted among 70 patients, age 5-25 years old with blood sugar concerns found biotin administration to serve as an adjuvant, which improved sugar management, as well as the balance of blood fats.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePantothenic Acid\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003ePantothenic acid and its biologically active derivative, CoA, are essential to the synthesis of fatty acids, membrane phospholipids, amino acids, steroid hormones, and energy production. 95% of CoA is found in the mitochondria. Pantothenic acid has also been shown to have a balancing effect on blood fats in animal studies and has also been shown in the research to support wound healing.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCholine Bitartrate\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThough not technically a B vitamin, choline is often associated with B-vitamins. 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Collagen is a special type of protein that accounts for as much as 30% of the body’s total protein. In particular, it’s a primary structural component of connective tissue. The amino acid composition of dietary collagens are very similar to those in human collagens, making dietary collagen peptides ideal for supporting normal body collagen turnover and renewal. Many individuals — the elderly, in particular — do not consume adequate protein. 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Unlike classic saw palmetto-based formulas, \u003cstrong\u003eOptimum Flow\u003c\/strong\u003e is not intended to affect the body’s levels of dihydrotestosterone (DHT), which is the active form of testosterone.*\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 10px;\"\u003e* These statements have not been evaluated by the Food and Drug Administration. 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This product’s primary active ingredient is Wellmune WGP®- a natural beta 1,3\/1,6 glucan derived from the cell wall of a proprietary strain of baker’s yeast (Saccharomyces cerevisiae).\u003c\/p\u003e\u003cp\u003eOnce swallowed, immune cells in the gastrointestinal tract take up Wellmune WGP® and transport it to immune organs throughout the body. Specific immune cells called macrophages digest Wellmune WGP® into smaller fragments and slowly release them over a number of days. The fragments then bind to neutrophils (white blood cells), via complement receptor 3 (CR3). 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[2] In a study of 54 firefighters given Wellmune WGP® or placebo, those who took\u003c\/p\u003e\u003cp\u003eWellmune WGP® experienced better physical health and nearly 25% reported fewer upper respiratory challenges. A 2013 study on healthy women given 250 mg Wellmune WGP® or placebo also found 10% fewer upper respiratory challenges compared to placebo; better well-being and mental and physical energy levels were also reported.[3] In another randomized, placebocontrolled, double-blind study on the effects of four weeks of 250 mg Wellmune WGP® or 250 mg per day of rice flour placebo on the physical and psychological health of those with seasonal discomfort symptoms, Wellmune WGP® improved symptoms, overall physical health and emotional well-being, compared to placebo.[4] Further research on medical students found a 22% reduction in the total number of days with upper respiratory symptoms in Wellmune WGP® group versus placebo. Finally, a 28-day lifestyle study found that participants taking Wellmune WGP® reported a 34% improvement in health scores after four weeks compared with the control group as well as increased vigor, and lower fatigue, confusion and tension. 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Taurine, a derivative of the sulfur-containing amino acid cysteine, is also important for synthesis of bile salts and helps stabilize cell membranes.* \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eGastrointestinal Support \u003c\/strong\u003eGinger root, included to support healthy digestion such as the release of bile from the gallbladder, acts at several sites to moderate PGE(2) production and support the normal response to inflammation.[3] Fiber (from inulin and flaxseeds) supports production of short-chain fatty acids as well as a healthy intestinal flora. MeadowPure™, an organic flaxseed complex, possesses excellent oxidative stability, supports antioxidant activity, and provides lignins, soluble fiber, and omega-3 and omega-6 essential fatty acids.[4] Glutamine plays a key role in healthy intestinal cell proliferation and gut barrier integrity, immune function, and normal tissue healing.*[1,2] \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDetoxification Support\u003c\/strong\u003e Ellagic acid (from pomegranate extract) prevents over-induction of CYP1A enzymes, works at the gene level to induce synthesis of glutathione-S-transferases and other phase II activities, binds directly to toxins, and protects DNA and hepatocytes.[5,6] Watercress is a rich source of beta-phenylethyl isothiocyanate (PEITC)—a versatile compound found to inhibit phase I enzymes and induce the phase II enzymes associated with biotransformation and excretion of toxins. Watercress has been found to contain even stronger phase II inducers known as 7-methylsulfinyheptyl and 8-methylsulfinyloctyl isothiocyanates as well.[7,8] Green tea catechins not only support antioxidant activity but also appear to act as modulators of phase I and phase II detoxification.[9] Choline is present to support lipid metabolism in the liver and can be converted to betaine, a methyl donor.*[10] The active, bioavailable form of B vitamins (pyridoxal-5’-phosphate (B6), 5-methyltetrahydrofolate (folate), methylcobalamin (B12)) and glycine all support amino acid conjugation and are vital for the detoxification of xenobiotics and xenoestrogens. 5-methyltetrahydrofolate (5-MTHF), methylcobalamin, betaine, and methylsulfonylmethane (MSM) are present to support methylation and detoxification. 5-MTHF supports healthy folate nutrition, especially in individuals with variations in folate metabolism. In Optimum Protein, 5-MTHF is provided as Quatrefolic® for enhanced stability, solubility, and bioavailability.*[11] Preventium®, a patented form of potassium hydrogen d-glucarate, supports glucuronidation. Sulfation is supported by MSM and sodium sulfate. Acetylation is supported by d-calcium pantothenate, pyridoxal-5’-phosphate, and magnesium. Several minerals in Optimum Protein are provided as Albion® mineral chelates and TRAACS® mineral amino acid chelates for enhanced gastrointestinal absorption and bioavailability.*[12] \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAntioxidant Support and Cytokine Balance\u003c\/strong\u003e Bioflavonoids, quercetin, rutin, and curcumin support antioxidant activity, counter free radicals, and support healthy eicosanoid and cytokine metabolism.[13,14] Curcumin has a long history of use for its support of a normal, healthy response to inflammation.[15] N-acetylcysteine (NAC) stimulates glutathione synthesis, enhances glutathione-S-transferase activity, and promotes detoxification.[16] Selenium glycinate provides support for glutathione metabolism and antioxidant protection.*\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDirections: \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eBlend, shake, or briskly stir 2 level scoops (54 g) into 10-12 ounces chilled, pure water (or mix amount for desired thickness) and consume once daily, or use as directed by your healthcare practitioner. 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Arbutin, particularly when combined with berberine sulfate, provides a powerful combination to help maintain healthy microbial balance in the urinary tract and bladder. In addition, marshmallow root soothes bladder and urinary tract discomfort. Celery seed extract and bladderwrack leaf are also included in \u003cstrong\u003eOptimum UT\u003c\/strong\u003e for their ability to promote a healthy urinary passage.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740319691000,"sku":"90","price":61.8,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/4742008831.png?v=1780291501"},{"product_id":"performance-plus-packs-multivitamin-and-mineral-blend","title":"Performance Plus Packs Multivitamin and Mineral Blend","description":"\u003cp\u003eIt is well-established that good nutrition promotes health, while nutritional deficiencies can lead to many chronic diseases. Yet, many people underestimate the importance of achieving proper levels of micronutrients each day. For the human body to complete vital daily tasks, it must be given a wide and complex variety of key micronutrients. Micronutrients play a role in strengthening immune function and converting food into energy. They detoxify chemicals and medications, and manufacture neurotransmitters, hormones and other key signaling molecules in the body. Micronutrients also maintain tissue repair and cell regeneration. Becoming deficient in any one of these essential vitamins or minerals can create a breakdown metabolic processes that safeguard health. \u003c\/p\u003e\u003cp\u003eComprehensive studies conducted by the United States Department of Agriculture have revealed the average American diet lacks micronutrients. Nutritional deficiencies may be caused by poor nutrient levels in the soil, food transport and storage methods, and food processing techniques. In addition, deficiencies can also be caused by highly processed and refined foods, food additives, medications, alcohol consumption, smoking, heavy metal exposure and high stress levels. Whatever the reason, nutrient deficiencies exist in a substantial portion of the U.S. population and, for select nutrients, more than 80% of Americans consume less than the recommended daily allowance (RDA). Although recommended nutrient intakes (e.g., %DV, DRIs, EARs, RDAs) have been established as minimum guidelines for healthy individuals, these guidelines were not designed to address the micronutrient needs of all individuals, especially those with chronic health concerns. While these guidelines can help prevent a severe nutrient deficiency, standards such as the RDA are not a reflection of optimal daily intake. For these reasons, a daily multivitamin is a prudent choice for most individuals. This product is a superior multivitamin designed to support the ideal daily intake of vitamins and minerals by providing a high-quality source of nutrients in the most bioavailable form.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBioavailability\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe importance of bioavailability is obvious. If consuming a multivitamin has little effect on improving the body’s nutrient balance, there is no reason to ingest it. Inferior multivitamin supplements often contain synthetic vitamin E in a dl-tocopherol form. This product contains natural d-alpha tocopherol, as well as mixed tocopherols, to enhance vitamin E availability and its free radical scavenging potential.3 Another sign of an inferior multivitamin is the use of cheap, poorly absorbed, rock-salt minerals like calcium carbonate and magnesium oxide. These mineral forms have slow and limited absorption relying on adequate stomach acid to promote passive diffusion into the body. What’s more, because they remain in the intestines longer, these forms can cause intestinal distress such as constipation (calcium carbonate) or diarrhea (magnesium oxide). This product provides a full spectrum of highly-absorbed, Albion® mineral chelates. Albion® is the world leader in manufacturing highly bioavailable mineral chelates, a specialized form of minerals bound to amino acids. This patented process creates natural mineral compounds which use active absorption mechanisms in the gastrointestinal tract to significantly enhance mineral absorption. Albion’s® mineral chelates have extensive clinical research proving their superior bioavailability, biologic activity, stability and tolerance.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eMetabolism \u0026amp; Energy Production\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eConverting food into cellular energy is a nutrient-intensive process. This product provides substantial levels of B vitamins, which are prime coenzymes for the Kreb’s cycle, the biochemical pathway responsible for maintaining energy production in the form of ATP (adenosine triphosphate). This product exclusively uses high-quality, USP-grade B vitamins ideal for those looking to boost their energy levels and support stressful lifestyles. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBroad Spectrum Antioxidant Support\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe body is constantly exposed to free radicals and relies heavily on its antioxidant reserve for protection. Free radicals are generated by metabolic by-products and environmental exposure such as UV rays from the sun, air pollution and radiation. This product contains a balanced spectrum of antioxidant vitamins such as vitamin C, mixed carotenoids, trace elements and nutrients that up-regulate antioxidant supporting pathways in the body. They work synergistically to regenerate each other and maintain adequate levels of protective antioxidants throughout the body. 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A colorful blend of organic health-promoting “superfoods” have been incorporated into this all-natural greens and reds drink for their phytonutrient content and support of antioxidant activity. Truebroc™ from broccoli seed extract is added for long-lasting antioxidant and detoxification support. Probiotics, fiber, and digestive enzymes augment gastrointestinal health, absorption, and utilization of nutrients in this comprehensive superfood blend. Organic flavoring and natural sweeteners (stevia and Luo Han Guo) make Power Greens not only healthful but great tasting, as well.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOrganic Fiber Blend \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eOrganic gum acacia, inulin, and flaxseeds provide a total of 3 g of dietary fiber per scoop of Power Greens to support gastrointestinal function and probiotic activity as well as to assure multiple health benefits from increased dietary fiber intake.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOrganic Greens and Veggies Blend \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eOrganic carrots, green cabbage, broccoli, beets, chlorella, and spinach provide concentrated sources of folate, chlorophyll, carotenoids, and a multitude of phytonutrients that promote health and fight disease. The greens in Power Greens are naturally alkalizing. An alkaline pH is needed for optimal metabolic, enzymatic, repair, and immune functions in the body.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAntioxidant Support\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eAscorbic acid, organic astragalus root, organic ginger root, and organic lycium berry extract provide an antioxidant rich foundation to protect tissues from free-radical damage and promote cellular health. OxyPhyte® Ultra Blend (white tea leaf extract, apple fruit extract, and rosemary leaf extract) provides antioxidant support. In fact, in a preclinical bioavailability trial, results suggested that this blend increased serum antioxidant levels in human subjects.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eOrganic Fruits and Berries Blend\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eOrganic apple juice powder, strawberry juice powder, sea buckthorn juice powder, açai, acerola fruit extract, plum fruit extract, and blueberry concentrates provide additional antioxidant capacity and health-promoting phytonutrients.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003etruebroc™ Broccoli Seed Extract \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003etruebroc provides a concentrated source of sulforaphane glucosinolate, also known as glucoraphanin. Glucoraphanin is a phytochemical precursor to sulforaphane, a naturally occurring isothiocyanate in broccoli that supports and promotes antioxidant and detoxification activity.Scientists at Johns Hopkins University School of Medicine identified glucoraphanin (GR) and sulforaphane (SFN) as the “missing links” that correlate a diet rich in cruciferous vegetables with the maintenance of good health. Broccoli sprouts and seeds provide higher concentrations of GR than the mature vegetable. Glucoraphanin is converted to SFN via the action of myrosinase, an enzyme in broccoli that is released during chewing, cutting, or slicing. Microorganisms can also convert GR to SFN; the presence of probiotics and broccoli in Power Greens may enhance this conversion in the body. Research suggests that GR and SFN provide long-lasting antioxidant and detoxification support that may improve overall health and well-being.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDigestive Support Blend \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eProbiotic organisms L acidophilus, B longum, L casei, and L rhamnosus are present to maintain a healthy gastrointestinal microflora. A healthy microflora provides gastrointestinal and immune support and helps to moderate and eliminate pathogenic bacteria. Digestive enzymes (protease, amylase, bromelain, cellulase, lactase, papain, and lipase) in Power Greens assist in the breakdown of carbohydrates, fats, proteins, and lactose to enhance nutrient digestion and availability. Power Greens can be consumed by itself or as an accompaniment to any smoothie or protein drink. The inclusion of phytonutrient-rich superfoods, OxyPhyte Ultra Blend, and truebroc creates an innovative and ideal formula for antioxidant support.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740320837880,"sku":"728b08230e8f","price":87.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2264108103.jpg?v=1780291504"},{"product_id":"renew-male-base-shilajit-and-eurycoma-longifolia","title":"Renew Male Base Shilajit and Eurycoma Longifolia","description":"\u003cp\u003eFive percent of males aged 40-50 years and as many as 70% of males over 70 years are confronted with “hypogonadism.” Low testosterone levels have been associated with a decline in libido, erectile dysfunction, lack of energy, less physical strength and endurance, loss of height, decreased enjoyment in life, low mood, feeling grumpy, falling asleep after dinner, and decreased work performance. Some studies suggest that low testosterone may also contribute to cognitive decline. Most circulating testosterone is bound to sex hormone-binding globulin (SHBG). Only the lesser amount of testosterone not bound to SHBG is considered bioavailable.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eShilajit\u003c\/strong\u003e is a naturally occurring, mineral-rich phytocomplex with many bioactive components, including fulvic acids. It comprises rock humus, rock minerals, and organic substances that have been compressed by layers of rock mixed with marine organisms and microbial metabolites. Shilajit has a rich history of use in Indian ayurvedic and siddha medicine as a health and wellness optimizer. It is known as a rasayana because of its rejuvenating qualities, which include heightening physical performance and relieving fatigue. According to an article in the American Journal of Clinical Nutrition, weightlifters use shilajit to promote better strength, recovery, and muscular hypertrophy and also to combat physical stress, but human data on these uses are lacking. Animal and human studies have documented the safety of shilajit. The oral median lethal dose (LD50) is \u0026gt; 200 grams, and chronic use at doses of 0.2–1.0 g\/kg body weight appear to be safe. Upwards of 50 studies on shilajit suggest that it has a positive effect on testosterone levels and adaptogenic, antioxidant, cytokine-balancing, immunomodulatory, and antidyslipidemic activities. Fulvic acid, the main bioactive component in shilajit, blocks tau proteins self-aggregation suggesting it may have a role in supporting cognition.\u003c\/p\u003e\u003cp\u003ePrimaVie® shilajit at a dose of 250 mg\/capsule consumed twice daily after major meals for 90 days was evaluated in 75 healthy male volunteers aged 45-55 for its testosterone secretion efficacy and its stimulation effects. This double-blind placebo-controlled study revealed that PrimaVie shilajit, when compared to placebo, significantly (P \u0026lt; 0.05) increased total testosterone, free testosterone, and dehydroepiandrosterone (DHEA). The levels of testosterone synthesis-supportive gonadotropic hormones were well-maintained. Another study further demonstrated the safety and also the spermatogenic nature of shilajit. Infertile males (n = 35) took 100 mg of PrimaVie shilajit twice daily after major meals for 90 days. At completion, 28 of the subjects had significant (P \u0026lt; 0.001) improvement compared to baseline values of factors related to fertility. Furthermore, at the study’s completion, the semen’s content of malondialdehyde (MDA), a marker for oxidative stress, was reduced. High-performance liquid chromatography (HPLC) revealed that the semen had constituents of PrimaVie shilajit. Compared to baseline, serum levels of testosterone rose 23.5% (P \u0026lt; 0.001) and follicle-stimulating hormone (FSH) rose 9.4% (P \u0026lt; 0.05.) Liver and kidney profiles were unchanged.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eEurycoma longifolia\u003c\/strong\u003e root (Malaysian ginseng) is considered a tonic and an adaptogen for supporting healthy libido, energy, sports performance, and weight management by promoting healthy testosterone levels and freeing testosterone from SHBG. Eurypeptides activate the CYP-17 enzyme, which plays a key role in production of DHEA, progesterone, testosterone, and pheromone via the metabolism of pregnenolone. A systemic review and meta-analysis of randomized controlled studies (n = 139) concluded that the herbal extract “may have clinical effect on erectile function. However, more efficacy trials are warranted to further support current evidence.” LJ100® Eurycoma longifolia is a root extract whose safety and efficacy is backed by animal and at least 12 human clinical studies. Compound isolation, a patented water-extraction process, and technologically advanced manufacturing methods ensure the purity of this ingredient and allow for the capture of the potent, biologically active eurypeptides. A randomized, placebo-controlled, two-month study focused on the outcomes of LJ100 on various parameters in male volunteers aged 38-58 who had varied health conditions and consumed either a placebo or 200, 400, or 600 mg of LJ100. The herb-consuming volunteers showed improvement in sexual desire and performance. Also, testosterone and DHEA levels were high-normal when compared to baseline; HDL cholesterol improved; those who had type-2 diabetes showed improvement in blood glucose levels; and insulin-like growth factors (IGF-1) were high-normal (lower levels of IGF-1 are correlated with higher body fat). Compared to those on placebo, the majority of the volunteers on LJ100 had high-normal levels of thyroxine suggesting higher metabolism. Blood and lipid panels and liver and renal function profiles, electrolytes, and various tumor markers including prostate specific antigen (PSA) were within normal range. The benefits of LJ100 are not limited to males or particular age groups. Two studies, one in middle-aged and one in senior males and females, demonstrated the herb’s promotion of healthy fitness, vitality, and vigor concomitant with an increase in free testosterone and a decline in SHBG.\u003c\/p\u003e\u003cp\u003eIn summary, it appears that the combination of these two herbs supports healthy testosterone levels in men and women which, in turn, supports vitality, virility, and vigor.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740321755384,"sku":"2","price":97.2,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2264112369.jpg?v=1780291506"},{"product_id":"sleep-performance-valerian-root-and-l-theanine","title":"Sleep Performance Valerian Root and L-Theanine","description":"\u003cp\u003e\u003cstrong\u003eDiscussion\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHuman Studies\u003c\/strong\u003e A Home Use Test (HUT) performed in 2005 among a target group of 61 men and women using SLEEP PRO II for two weeks yielded very positive results.\u003csup\u003e[1]\u003c\/sup\u003e Seventy-four percent of respondents used the product according to the directions: Take seven or more capsules during the two-week test period. Of these respondents,\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e83% said SLEEP PRO II helped them relax*\u003c\/li\u003e\n\u003cli\u003e91% said SLEEP PRO II helped reduce fatigue due to lack of sleep*\u003c\/li\u003e\n\u003cli\u003e91% said SLEEP PRO II helped ensure a good night’s sleep*\u003c\/li\u003e\n\u003cli\u003e82% said SLEEP PRO II is an essential item to have on hand*\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eAn open-label, single-center, observational survey that included 295 people (ages 18-87) with sleep difficulties was performed to obtain a subjective evaluation of the tolerability and effectiveness of SLEEP PRO II.\u003csup\u003e[2]\u003c\/sup\u003e Self-reported sleep difficulties included problems falling asleep, multiple wakings, and next-day tiredness due to a lack of sleep. Patients taking at least one 365 mg capsule of SLEEP PRO II one hour before going to bed every night for at least two weeks experienced the following:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e86% considered SLEEP PRO II relaxing*\u003c\/li\u003e\n\u003cli\u003e82.8% said SLEEP PRO II assisted in a restful sleep*\u003c\/li\u003e\n\u003cli\u003e82.8% said SLEEP PRO II was effective in reducing fatigue due to lack of sleep*\u003c\/li\u003e\n\u003cli\u003eNo significant adverse events\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eSLEEP PRO II (known as SEDITOL®) is a blend of a patented extract of Magnolia officinalis bark and a proprietary extract of Ziziphus spinosa seed. These herbs have been traditionally used in Asia for qì stagnation, for mild anxiety and nervousness, and to support normal, uninterrupted sleep.*\u003csup\u003e[3-5] \u003c\/sup\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eMagnolia officinalis\u003c\/strong\u003e Magnolia bark is rich in a biphenol compound called honokiol and its isomer magnolol. In experimental animal studies, these compounds have been shown to enhance the activity of gamma-aminobutyric acid (GABA) A receptors and GABA binding, which may help the body cope with the neurologic effects emotions can have on behavior and well-being.\u003csup\u003e[4,6]\u003c\/sup\u003e Honokiol, administered by intraperitoneal injection in mice, was shown to promote NREM (non-rapid eye movement) sleep by modulating the benzodiazepine site of the GABA (A) receptor.\u003csup\u003e[5]\u003c\/sup\u003e And, in an experimental animal model of chronic mild stress, a mixture of honokiol and magnolol supported normal levels of 5-hydroxytryptamine (5-HT) and its metabolite 5-hydroxyindoleacetic acid (5-HIAA) in various brain regions. The combination also promoted healthy corticosterone levels and platelet adenylyl cyclase (AC) activity. Researchers suggest that these findings provide a basis for further study into the influence of magnolol and honokiol on the serotonergic system, the HPA (hypothalamic-pituitary-adrenal) axis, and the AC-cAMP pathway in relation to mood and emotional behavior.*\u003csup\u003e[7]\u003c\/sup\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eZiziphus spinosa\u003c\/strong\u003e A primary use of Z spinosa seeds in Traditional Chinese Medicine is to support calmness and help individuals with occasional sleeplessness.\u003csup\u003e[8,9]\u003c\/sup\u003e In an experimental animal model, saponins and flavonoids extracted from the seeds showed a significant relaxing effect and helped prolong sleeping time.\u003csup\u003e[8]\u003c\/sup\u003e To investigate potential mechanisms, researchers tested the influence of spinosin—a flavonoid derived from ziziphus seeds—on pentobarbital-induced sleep in mice. They concluded that it potentiated sleep via a serotonergic mechanism.*\u003csup\u003e[10] \u003c\/sup\u003e\u003c\/p\u003e\u003cp\u003eKoetter et al\u003csup\u003e[3]\u003c\/sup\u003e studied the interactions of magnolia and ziziphus extracts with selected central nervous system receptors in a series of assays. Interactions with the adenosine A1 receptor, dopamine transporter and dopamine D5 receptor (antagonist activity), serotonin receptors (5-HT1B and 5-HT6 antagonist activity), and the GABA benzodiazepine receptor were demonstrated. It is suggested that these findings provide some insight into the combined activity of these extracts.*\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDirections\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eTake one to two capsules before bedtime, or as directed by your healthcare practitioner.\u003c\/p\u003e\u003cp\u003eConsult your healthcare practitioner before use. Do not use if pregnant or lactating. Do not use if tamper seal is damaged.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e1. Seditol sleep supplement. HUT: Final report. TRG Study #82-05013. Nanuet, NY: Target Research Group; April, 2005. Study on file.\u003c\/p\u003e\u003cp\u003e2. LaValle J, Pelletier M, LaValle L, et al. A proprietary blend of Magnolia and Ziziphus extracts assists with sleep: an open-label assessment.\u003c\/p\u003e\u003cp\u003e3. Koetter U, Barrett M, Lacher S, et al. Interactions of Magnolia and Ziziphus extracts with selected central nervous system receptors. J Ethnopharmacol. 2009 Jul 30;124(3):421-25. [PMID: 19505549]\u003c\/p\u003e\u003cp\u003e4. Alexeev M, Grosenbaugh DK, Mott DD, et al. The natural products magnolol and honokiol are positive allosteric modulators of both synaptic and extra-synaptic GABA(A) receptors. Neuropharmacology. 2012 Jun;62(8):2507-14. [PMID: 22445602]\u003c\/p\u003e\u003cp\u003e5. Qu WM, Yue XF, Sun Y, et al. Honokiol promotes non-rapid eye movement sleep via the benzodiazepine site of the GABA(A) receptor in mice. Br J Pharmacol. 2012 Apr 27. doi: 10.1111\/j.1476-5381.2012.02010.x. [Epub ahead of print] [PMID: 22537192]\u003c\/p\u003e\u003cp\u003e6. Squires RF, Ai J, Witt MR, et al. Honokiol and magnolol increase the number of [3H] muscimol binding sites three-fold in rat forebrain membranes in vitro using a filtration assay, by allosterically increasing the affinities of low-affinity sites. Neurochem Res. 1999 Dec;24(12):1593-602. [PMID: 10591411]\u003c\/p\u003e\u003cp\u003e7. Xu Q, Yi LT, Pan Y, et al. Antidepressant-like effects of the mixture of honokiol and magnolol from the barks of Magnolia officinalis in stressed rodents. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Apr 1;32(3):715-25. [PMID: 18093712]\u003c\/p\u003e\u003cp\u003e8. Jiang JG, Huang XJ, Chen J, et al. Comparison of the sedative and hypnotic effects of flavonoids, saponins, and polysaccharides extracted from Semen Ziziphus jujube. Nat Prod Res. 2007 Apr;21(4):310-20. [PMID: 17479419]\u003c\/p\u003e\u003cp\u003e9. Peng WH, Hsieh MT, Lee YS, et al. Anxiolytic effect of seed of Ziziphus jujuba in mouse models of anxiety. J Ethnopharmacol. 2000 Oct;72(3):435-41. [PMID: 10996283]\u003c\/p\u003e\u003cp\u003e10. Wang LE, Bai YJ, Shi XR, et al. Spinosin, a C-glycoside flavonoid from semen Zizhiphi Spinozae, potentiated pentobarbital-induced sleep via the serotonergic system. Pharmacol Biochem Behav. 2008 Sep;90(3):399-403. [PMID: 18466960]\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDoes Not Contain\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eWheat, gluten, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically-modified organisms (GMOs) artificial colors, artificial sweeteners, or preservatives.\u003c\/p\u003e\u003ctable class=\"ecwid-description-table\"\u003e\u003ctbody\u003e\u003ctr\u003e\u003cth\u003e\u003cstrong\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/strong\u003e\u003c\/th\u003e\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740322050296,"sku":"a5d069f3dad7","price":70.2,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2253596243.jpg?v=1780291507"},{"product_id":"spore-defend-probiotic","title":"Spore Defend Probiotic","description":"\u003cp\u003e\u003cstrong\u003eSpore Defend\u003c\/strong\u003e is a spore-based, broad-spectrum probiotic formula designed to promote a healthy gut microflora, protect mucosal integrity,\u003cbr\u003e\u003c\/p\u003e\u003cp\u003eProbiotics have been extensively studied and are characterized as having broad GI and immune benefits. Probiotics are live organisms and must be shelf stable through the expiration date, so they can be precisely delivered to the intestinal tract to have maximum benefit. \u003cem\u003eBacillus \u003c\/em\u003espores remain dormant in harsh environments until they reach more favorable environments like the human gastrointestinal tract. The combination of specific strains, particularly \u003cem\u003eBacillus coagulans\u003c\/em\u003e, \u003cem\u003eBacillus clausii\u003c\/em\u003e, and \u003cem\u003eBacillus subtilis\u003c\/em\u003e, relieve symptoms for common GI complaints and reinforce healthy gut function.\u003c\/p\u003e\u003cdiv\u003eIn the search for innovative ways to improve microbiome diversity, we have combined our blend of spore-forming probiotics alongside immunoglobulins uniquely shown to bind to bacteria and toxins, driving immune response. IgG helps to maintain a healthy intestinal immune system by binding a broad range of microbes and toxins within the gut lumen.\u003c\/div\u003e\u003cdiv\u003e\u003cstrong\u003eSuggested Use:\u003c\/strong\u003e\u003c\/div\u003e\u003cdiv\u003e\n\u003cstrong\u003e\u003c\/strong\u003e3 capsules per day or as recommended by your health care professional.\u003cspan\u003e\u003c\/span\u003e\n\u003c\/div\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740322607352,"sku":"79","price":81.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2225778349.jpg?v=1780291508"},{"product_id":"thyroid-support-ii-nac-l-tyrosine-and-ashwagandha","title":"Thyroid Support II NAC, L-Tyrosine and Ashwagandha","description":"\u003cp\u003eThe thyroid gland, located in the neck below the Adam’s apple, produces T4 and T3 hormones that regulate cell metabolism. In this process, thyroxine is converted into the metabolically active hormone T3. Thyroid hormones are required for mitochondrial metabolism in every cell in the body. Therefore, a deficiency of thyroid hormones can affect virtually all bodily functions, including metabolic rate, reproduction, hormone production, and brain function, as well as musculoskeletal, psychological and cardiovascular health.1 Lifestyle factors, environmental toxins and nutrient deficiencies can negatively impact thyroid hormone production. A number of nutrients are required to produce thyroid hormones and to help convert T4 into T3. These nutrients include L-tyrosine, iodine, selenium, zinc and vitamin A. A deficiency in any of these nutrients can cause the thyroid to under-function. Heavy metals, such as mercury, lead and cadmium, as well as other chemical contaminants, can also block the conversion of T4 to T3. In addition, long-term stress can lead to increased production of the adrenal hormone cortisol. Excessive levels of cortisol can block the conversion of T4 to T3 and also increase the production of reverse T3 (RT3). RT3 is an isomer of triiodothyronine that competes with T3 at the receptor sites. Conversely, exercise positively impacts the thyroid gland by stimulating hormone secretion and increasing tissue sensitivity to thyroid hormones.1 (See Figure 1). \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eVitamins and Minerals † \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThyroid hormones are made from amino acid L-tyrosine and iodine. Iodine is an essential trace mineral and is necessary for the synthesis of thyroid hormones, as it is one of the most important components of the hormones T4 and T3. The thyroid gland absorbs iodine from the blood and incorporates it into thyroid hormones. In addition to supporting thyroid hormone production, research shows iodine acts as an antioxidant, supporting a healthy thyroid gland and protecting a variety of tissues, including mammary tissue, the eyes and gastrointestinal lining.2 Normal thyroid status is dependent on adequate levels of many trace minerals for the synthesis and metabolism of thyroid hormones. The minerals zinc, copper and selenium are required cofactors for the enzymes that convert T4 to T3. Selenium deficiency has been shown to contribute to decreased T4 to T3 conversion.3 Supplementation of selenium can also help decrease thyroperoxidase (TPO) antibodies in thyroid autoimmunity.3 Supplementation with zinc has been shown to restore T3 levels in patients with normal T4 and low T3, demonstrating its role in the conversion process.4 Vitamin A and vitamin E are also necessary for normal thyroid hormone manufacturing. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAntioxidants (Turmeric, Vitamins C and E, and N-Acetyl Cysteine)† \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eIncreased free radical activity can compromise healthy T4 to T3 conversion. N-acetyl cysteine (NAC), a precursor to the body’s master antioxidant glutathione, boosts thyroid health by accelerating antioxidant activity in the thyroid gland. In a randomized, multicenter clinical trial, the effects of NAC administration were examined in patients with low T3 and high RT3 levels. RT3 decreased in a time-dependent fashion in NACtreated patients, whereas no significant changes in serum RT3 levels were observed in the placebo group. Additionally, the T3 to RT3 ratio increased progressively in NAC-treated patients, whereas no changes were seen in the placebo group.5 Turmeric (Curcuma longa), along with the antioxidants vitamin C and E, has been shown to promote a healthy thyroid gland due to direct antioxidant activity. In animal studies, turmeric and these antioxidants were studied to observe the protective effects on thyroid health. In this study, rats that had been treated with a chemical that increased thyroid weights showed decreased T4 and T3 as compared to controls. In the treatment group, rats receiving vitamin C, E and turmeric showed reduced weights in the thyroid gland and less suppression of T4 and T3 levels. The researchers suggested that the positive effects of the curcumin, vitamin C and vitamin E combination could be due to the direct involvement of antioxidants in the thyroid gland. 6\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAshwagandha † \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eAshwagandha (Withania somnifera) has been used in Aryuvedic and indigenous medical systems for over 3,000 years and has been examined in research studies for its stresslowering effects.7 Ashwagandha has been found to exhibit GABA agonist activity, which accounts for its ability to relax the nervous system. Ashwagandha may also stimulate thyroid activity indirectly, via its effects on cellular antioxidant systems, specifically by increasing the antioxidant enzymes superoxide dismutase and catalase and reducing lipid peroxidation.8 In studies using mice, the effects of administration of Withania somnifera root extract (1.4 g\/kg of body weight for 20 days) demonstrated an increase in serum T4 concentrations.8,9 \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eGuggulipid (Commiphora mukul) † \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThe gum resin of the guggul plant has been used in Ayurvedic medicine in India for nearly 3,000 years. Guggulipid has been shown to support thyroid function, primarily by decreasing lipid peroxidation in the liver, the principal site of T3 generation. Guggul extract has also been shown to have thyroid-stimulating action by increasing iodine uptake by the thyroid gland and increasing the activities of thyroid peroxidase and protease.10,11 In animal studies using mice, the effects of guggulu, the gum resin of Commiphora mukul, were examined. A chemical that induced hypothyroidism was administered simultaneously along with guggulu (200 mg\/ kg of body weight per day for 30 days). In this study, it was found that treatment with guggulu decreased lipid peroxidation while increasing the activity of sodium oxidase dismutase and catalase.1\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDirections: \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e4 capsules per day or as recommended by your health care professional.\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740323131640,"sku":"3a23bdeef06b","price":78.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2253596268.jpg?v=1780291509"},{"product_id":"ut-optimum-flow","title":"UT Optimum Flow","description":"\u003cp\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003cstrong\u003eUT Optimum Flow\u003c\/strong\u003e is a powerful blend of whole fruit cranberry extract and D-mannose, which are designed to promote a healthy urinary tract.* Cranberry is one of the most widely studied fruits used in traditional medicine for supporting urinary tract health. Unlike many commercially available cranberry products, which are made from juice or contain individual isolated, health-promoting phytochemicals, the cranberry extract in \u003cstrong\u003eUT Optimum Flow\u003c\/strong\u003e is made from the whole fruit — juice, skins, flesh, and seeds — and therefore contains the full complement of phytochemicals, organic acids, fatty acids, and phenolics. Mannose is a type of sugar found in various fruits and vegetables. The naturally occurring isomer, D-mannose, is similar in structure to certain urinary tract receptors, and thus, functions in a way that helps maintain a healthy microbial environment in the urinary tract.* Although mannose is a sugar, it is eliminated from the body instead of impacting calorie intake or metabolism, and it does not interfere with blood sugar regulation.*\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 10px;\"\u003e* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740323721464,"sku":"94","price":62.1,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/4918899873.png?v=1780291511"},{"product_id":"ut-support-cranberry-and-hibiscus","title":"UT Support Cranberry and Hibiscus","description":"\u003cp\u003eThe urinary tract is made up of the kidneys, bladder, and the tubes leading to and from these organs, the ureters and the urethra, and is responsible for producing urine and eliminating it from the body. As an important organ of elimination, a healthy urinary system is essential to the health of the entire body. Many individuals including pregnant women, and the elderly may benefit from additional support for the urinary tract. The Cran-Max® in this product formula is made of 100% cranberry fruit solids concentrated through a proprietary process by using 34 pounds of whole fresh cranberries to produce one pound of Cran-Max®. This process intensifies the natural benefits of the whole cranberry, without the use of any solvents, preservatives, sugars, water, flavorings or color. Together with UTI Rose™ and dandelion leaf, this product offers a full spectrum of kidney and urinary tract support, promoting microbial balance, healthy detoxification and urine excretion. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eCranberries\/Cran-Max® \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eCranberry juice has been used historically as a remedy for urinary tract health. The mechanism of action of cranberry juice and its extracts is the inhibition of microbial binding to host cell surface membranes. In vitro studies have observed it to promote healthy microbial balance facilitated by proanthocyanidins (PAC), which impact bacterial adherence and maintain the microbial health of the urinary tract. A recent meta-analysis of 10 clinical trials and 1,494 subjects, showed supplementation of cranberry-containing products supported urinary tract health and urine flow, in women and children, showing greater benefit for cranberry users by 38%. A meta-analysis of the results of four randomized controlled clinical trials, found prophylactic use of cranberry significantly supported urinary tract health over a 12-month period, compared with placebo. In another published clinical study, more patients experienced better urinary tract health markers in the Cran-Max® supplemented group, compared to the group given dry cranberry powder. \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHibiscus sabdariffa\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eH.sabdariffa extracts have long been used in herbal teas and for urinary tract support. H.sabdariffa calyx in a 10:1 extract (patented UTI Rose™ extract) includes compounds that promote microbial balance, and prevent bacteria from adhering to the bladder wall, including substantial amounts of flavonoids, sambubiocides, anthocyanidins, proanthocyanidins and chlorogenic acids. In addition, other ingredients such as polysaccharides and a high concentration of simple organic acids provide urinary tract support. An in vitro study on Hibiscus calyx and protocatechuic acid has shown its ability to promote microbial balance, mediated by protocatechuic acid content and a six-month, double-blind, placebo controlled study, found 200 mg of H.sabdariffa extract taken once a day, significantly promoted urinary tract health by 77%.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDandelion Leaf Extract\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eDandelion leaf has a history of use in various preparations including infusions, extracts, and fresh expressed juice for improving urinary tract function. A clinical study of 17 participants given an extract of T. officinale fresh leaf, found it acts as a natural diuretic to increase the frequency and excretion ratio of fluids in these healthy subjects.\u003c\/p\u003e\u003cp\u003eDirections 2 capsules per day or as recommended by your health care professional. \u003c\/p\u003e","brand":"Causenta","offers":[{"title":"Default Title","offer_id":48740324442360,"sku":"5b3997fca69a","price":46.2,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0824\/3078\/7832\/files\/2253572269.jpg?v=1780291512"}],"url":"https:\/\/causenta.com\/collections\/vitamins-supplements.oembed","provider":"Causenta","version":"1.0","type":"link"}